Formaldehyde

Formaldehyde

SCHEMBL4563394

C=O.CC(=O)CCC=C(C)C

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.58
ATM Q13315 1/20 0.58
POLB P06746 1/20 0.56
KMT2A Q03164 3/20 0.50
TSHR P16473 1/20 0.50
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 3/20 0.47
MEN1 O00255 2/20 0.46
CYP3A4 P08684 2/20 0.46
FNTA P49354 2/20 0.45
FNTB P49356 2/20 0.45
MAPT P10636 2/20 0.44
UGT1A1 P22309 1/20 0.44
SQLE Q14534 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157735 0.95
SCHEMBL28009409 0.95 KDM4E (0.62) KDM4EATMPOLBKMT2ATSHR
Bicarbonate SCHEMBL28331616 0.90 KDM4E (0.64) KDM4EATMPOLBKMT2ATSHR
Hydrazine SCHEMBL17870970 0.90 POLB (0.61) KDM4EATMPOLBKMT2ATSHR
Formic Acid SCHEMBL28331617 0.87 KDM4E (0.56) KDM4EATMPOLBKMT2ATSHR
SCHEMBL14236831 0.85 KMT2A (0.73) KDM4EATMPOLBKMT2AALDH1A1
SCHEMBL3111482 0.85 KMT2A (0.73) KDM4EATMPOLBKMT2AALDH1A1
SCHEMBL790270 0.85 KMT2A (0.73) KDM4EATMPOLBKMT2AALDH1A1
SCHEMBL7946216 0.85 KMT2A (0.73) KDM4EATMPOLBKMT2AALDH1A1
SCHEMBL14236792 0.85 KMT2A (0.73) KDM4EATMPOLBKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019050803-A1 SYSTEMS AND METHODS FOR COPPER ETCH RATE MONITORING AND CONTROL UNIVERSITY OF NORTH TEXAS (US) 2019-03-14 WO disclosed
EP-2975934-A1 BLENDS AND THEIR USE IN THE CONTROLLING AND/OR TRAPPING OF MOTHS Bioforsk (NO) 2016-01-27 EP disclosed
WO-2014147110-A1 BLENDS AND THEIR USE IN THE CONTROLLING AND/OR TRAPPING OF MOTHS BIOFORSK (THE NORWEGIAN INSTITUTE FOR AGRICULTURAL AND ENVIRONMENTAL RESEARCH) (NO) 2014-09-25 WO disclosed
US-7638658-B2 Ethynylation process DSM IP ASSETS B.V. (NL) 2009-12-29 US disclosed
EP-1532092-B1 ETHINYLATION PROCESS DSM IP ASSETS BV (NL) 2008-11-05 EP disclosed
EP-1432667-B1 ETHYNYLATION PROCESS DSM IP ASSETS BV (NL) 2007-11-28 EP disclosed
US-20050240066-A1 Ethynylation process DSM IP ASSETS B.V. (NL) 2005-10-27 US disclosed
US-6949685-B2 reacting formaldehydes, acyclic aldehydes or ketones with acetylene in the presence of ammonia and ion exchange resins, to form acyclic unsaturated alcohols used as intermediates for vitamins and carotenoids; alkylynation DSM IP ASSETS B.V. (NL) 2005-09-27 US disclosed
EP-1532092-A1 ETHYNYLATION PROCESS DSM IP Assets B.V. (NL) 2005-05-25 EP disclosed
US-20050059844-A1 Ethynylation process DSM IP ASSETS B.V. (NL) 2005-03-17 US disclosed
EP-1432667-A1 ETHYNYLATION PROCESS DSM IP Assets B.V. (NL) 2004-06-30 EP disclosed
WO-2004018400-A1 ETHYNYLATION PROCESS DSM IP ASSETS B.V. (NL) 2004-03-04 WO disclosed
WO-2003029175-A1 ETHYNYLATION PROCESS DSM IP ASSETS B.V. (NL) 2003-04-10 WO disclosed
US-6307106-B1 REACTING THE CORRESPONDING ALPHA,BETA-UNSATURATED ALCOHOLS WITH ALKYL ACETOACETATES IN A CARROLL REACTION IN THE PRESENCE OF AN ORGANIC ALUMINUM COMPOUND AS CATALYST WITH CONTINUOUS REMOVAL BY DISTILLATION OF THE ALKANOL ELIMINATED BASF AKTIENGESELLSCHAFT (DE) 2001-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240066-A1 Ethynylation process ADH1A, ADH4, ADH1C KDM4E 2441/4885ATM 1252/4885POLB 856/4885
US-20050059844-A1 Ethynylation process F12, CPS1, TTPA KDM4E 932/4885ATM 734/4885POLB 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.