SCHEMBL456378

SCHEMBL456378

CC(c1ccccc1)[PH](=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
ADRA2C P18825 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ADRA2A P08913 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP2D6 P10635 2/20 0.41
SRC P12931 1/20 0.41
ALDH1A1 P00352 2/20 0.40
ALOX5 P09917 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA1A P35348 1/20 0.39
RGS12 O14924 1/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20513971 0.98 LMNA (0.41) LMNAADRA2CKDM4EADRA2AHIF1A
Hydrochloric Acid SCHEMBL10914576 0.98 ALDH1A1 (0.43) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL19974050 0.79 ACHE (0.41) LMNAALDH1A1ALOX5KMT2A
SCHEMBL21461719 0.79 LMNA (0.40) LMNAADRA2CKDM4EADRA2AHIF1A
Isopropylbenzene SCHEMBL27855834 0.78 CRHBP (0.43) LMNAADRA2CKDM4EADRA2AHIF1A
Phosphonic Acid SCHEMBL11578743 0.78 DAO (0.46) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL20514226 0.77 ACHE (0.40) LMNAALDH1A1ALOX5
SCHEMBL16700064 0.77 ALDH1A1 (0.36) KDM4EHIF1AALDH1A1KMT2ACYP3A4
SCHEMBL10815881 0.76 TSHR (0.40) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL9242052 0.75 SRC (0.44) LMNACYP2D6SRCMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2026-04-09 US claimed
CN-114478624-B Telomer of diethyl aluminum phosphinate and preparation method thereof 兰州瑞朴科技有限公司 2024-07-02 CN claimed
CN-113518803-B Waterproof property of organic external wall 罗门哈斯公司 2023-09-15 CN claimed
WO-2023138015-A1 ALUMINUM DIETHYLPHOSPHINATE FLAME RETARDANT AND PREPARATION METHOD THEREFOR 兰州瑞朴科技有限公司 2023-07-27 WO claimed
EP-3941982-B1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2023-06-21 EP claimed
US-20220154010-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM AND HAAS COMPANY (US) 2022-05-19 US claimed
CN-114478624-A Telomer of aluminum diethylphosphinate and preparation method thereof 兰州瑞朴科技有限公司 2022-05-13 CN claimed
EP-3941982-A1 WATER RESISTANCE FOR ORGANIC FACADES Rohm and Haas Company (US) 2022-01-26 EP claimed
CN-113929967-A Phosphorus-nitrogen double salt and preparation method thereof, flame retardant and application thereof 浙江新化化工股份有限公司 2022-01-14 CN claimed
CN-113518803-A Water resistance of organic outer wall 罗门哈斯公司 2021-10-19 CN claimed
CN-107641136-B Diorganophosphinate salts, method for the production thereof and use thereof 科莱恩塑料和涂料有限公司 2020-04-10 CN claimed
EP-3487957-A1 FLAME RETARDANT MIXTURES, THE PRODUCTION AND THE USE THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-05-29 EP claimed
EP-3487861-A1 DIORGANYLPHOSPHINIC ACID SALTS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-05-29 EP claimed
EP-3487956-A1 FLAME PROTECTION AGENT MIXTURES, THEIR PREPARATION AND THEIR USE Clariant Plastics & Coatings Ltd (CH) 2019-05-29 EP claimed
EP-3380551-A1 POLYMERIC FLAME RETARDANT MIXTURES Clariant Plastics & Coatings Ltd (CH) 2018-10-03 EP claimed
CN-108291050-A POLYMERIC FLAME RETARDANT MIXTURES 科莱恩塑料和涂料有限公司 2018-07-17 CN claimed
CN-107641136-A Two organic group phosphinates, Its Preparation Method And Use 科莱恩塑料和涂料有限公司 2018-01-30 CN claimed
CN-107641218-A Flame retardant mixtures, their preparation and their use 科莱恩塑料和涂料有限公司 2018-01-30 CN claimed
CN-107637605-A Flame-retardant mixture, its preparation and application thereof 科莱恩塑料和涂料有限公司 2018-01-30 CN claimed
CN-105017311-B Rare earth phenylethyl phosphinate, and synthesis method and application thereof 广东华南精细化工研究院有限公司 2017-04-19 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ERG, LATS2, FTO LMNA 1575/4885ADRA2C 2837/4885KDM4E 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.