Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906148 | 0.81 | KIF11 (0.44) | MEN1KMT2AKIF11RIPK1GAA | |
| SCHEMBL7809644 | 0.70 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27641846 | 0.70 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1525128 | 0.69 | CA1 (0.41) | MEN1KMT2AKIF11RIPK1GAA | |
| SCHEMBL11699226 | 0.69 | ALDH1A1 (0.50) | TAS2R14MEN1KMT2AMAPTTSHR | |
| SCHEMBL31320998 | 0.69 | RIPK1 (0.44) | MEN1KMT2AKIF11RIPK1GAA | |
| SCHEMBL19319661 | 0.69 | KDM4E (0.43) | GRIK1MEN1KMT2AMPOMAPT | |
| SCHEMBL8625772 | 0.68 | ALDH1A1 (0.41) | TAS2R14KMT2AMAPTTDP1SMN1; SMN2 | |
| SCHEMBL5898552 | 0.68 | SCN5A (0.48) | MEN1KMT2AKIF11MAPTRIPK1 | |
| SCHEMBL14234964 | 0.68 | ALDH1A1 (0.48) | MEN1KMT2AMAPTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109615-A1 | SUBSTITUTED PYRANO [2, 3 - B]PYRIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2009-10-21 | — | — | EP | disclosed |
| EP-2094664-A2 | A NEW PROCESS FOR THE PREPARATION OF MONTELUKAST | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008094476-A1 | SUBSTITUTED PYRANO [2, 3 - B] PYRIDINE DERIVATIVES AS CANNABINOID -1 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008049922-A2 | A NEW PROCESS FOR THE PREPARATION OF MONTELUKAST | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2008-05-02 | — | — | WO | disclosed |