Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898573 | 0.83 | OGG1 (0.41) | SCN5ASCN9AGAAKIF11SMN1; SMN2 | |
| SCHEMBL6014096 | 0.82 | PARP1 (0.49) | SCN5ASCN9APARP1GAACA1 | |
| SCHEMBL3837958 | 0.81 | MAPT (0.55) | SCN5ASCN9AKIF11KMT2AL3MBTL1 | |
| SCHEMBL13946506 | 0.81 | MAPT (0.55) | SCN5ASCN9AKIF11KMT2AL3MBTL1 | |
| SCHEMBL13946510 | 0.81 | MAPT (0.55) | SCN5ASCN9AKIF11KMT2AL3MBTL1 | |
| SCHEMBL4001103 | 0.81 | SCN5A (0.48) | SCN5ASCN9AGAASMN1; SMN2KMT2A | |
| SCHEMBL16056375 | 0.76 | KMT2A (0.60) | PARP1GAACA1CA2CA5A | |
| SCHEMBL5898541 | 0.76 | PTPRC (0.52) | SCN5ASCN9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL1525128 | 0.75 | CA1 (0.41) | PARP1GAACA1CA2CA5A | |
| SCHEMBL31292746 | 0.74 | RIPK1 (0.42) | PARP1GAACA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
| WO-2003091201-A1 | DL-HYDROXY-ALKYL-PHENYLAMIDES HAVING ANTICONVULSIVE ACTIVITY | MEZA TOLEDO SERGIO ENRIQUE (MX) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | GABRB2, HRH3, HRH4 | SCN5A 338/4885SCN9A 903/4885PARP1 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.