Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF1 | P18846 | 7/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | XPO1 | O14980 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473934 | 0.78 | ATF1 (0.62) | ATF1NFKB1MAPTXPO1GAA | |
| SCHEMBL8398360 | 0.76 | NFKB1 (0.56) | ATF1NFKB1MAPTXPO1GAA | |
| SCHEMBL30110408 | 0.70 | NFKB1 (0.46) | ATF1NFKB1MAPTXPO1GAA | |
| SCHEMBL1602748 | 0.70 | NFKB1 (0.46) | ATF1NFKB1MAPTXPO1GAA | |
| SCHEMBL21746957 | 0.69 | NFKB1 (0.55) | ATF1NFKB1MAPTXPO1GAA | |
| SCHEMBL23146727 | 0.69 | NPC1 (0.53) | NFKB1MAPTSMN1; SMN2NPC1CASP3 | |
| SCHEMBL8398500 | 0.68 | NFKB1 (0.53) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL31584477 | 0.68 | TSHR (0.45) | ATF1NFKB1MAPTGAASMN1; SMN2 | |
| SCHEMBL21554055 | 0.68 | TSHR (0.45) | ATF1NFKB1MAPTGAASMN1; SMN2 | |
| SCHEMBL5413769 | 0.66 | YTHDC1 (0.41) | ATF1NFKB1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009157014-A2 | A PROCESS FOR PREPARING HMG-COA REDUCTASE INHIBITORS AND INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |