Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735509 | 0.86 | PRMT1 (0.59) | CASP6PTPN11NSD2DUSP3PTPN5 | |
| SCHEMBL27360806 | 0.85 | SLC6A2 (0.59) | PTPN11SLC6A2P2RY14PRMT1MAPT | |
| SCHEMBL3420178 | 0.81 | SLC6A2 (0.56) | PTPN11SLC6A2P2RY14PRMT1MAPT | |
| SCHEMBL2186294 | 0.79 | SLC6A2 (0.54) | SLC6A2P2RY14PRMT1MAPTKDM4E | |
| SCHEMBL12193501 | 0.79 | SLC6A2 (0.54) | SLC6A2P2RY14PRMT1MAPTKDM4E | |
| SCHEMBL9119115 | 0.78 | PTPN1 (0.53) | PLAUMAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4395647 | 0.77 | LMNA (0.55) | CASP6PTPN11NSD2DUSP3PTPN5 | |
| SCHEMBL163553 | 0.76 | PRMT1 (0.56) | SLC6A2P2RY14PRMT1MAPTKDM4E | |
| SCHEMBL30514356 | 0.75 | BCL2L1 (0.67) | PTPN11SLC6A2P2RY14PRMT1MAPT | |
| SCHEMBL21979549 | 0.75 | BCL2L1 (0.67) | PTPN11SLC6A2P2RY14PRMT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306201-A1 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306201-A1 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306201-A1 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2007149782-A2 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007149782-A2 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306201-A1 | SELECTIVE INHIBITORS FOR TRANSFERASES | TYMP, PCNA, TK1 | CASP6 4050/4885PTPN11 3419/4885NSD2 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.