Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249660 | 0.89 | DHPS (0.57) | DHPSSTING1KDM4CEGLN1LMNA | |
| SCHEMBL1159186 | 0.76 | PARP1 (0.53) | KDM4CPARP1 | |
| SCHEMBL29809414 | 0.72 | ACHE (0.59) | DHPSEGLN1LMNAKDM4EHTT | |
| SCHEMBL1757848 | 0.72 | ACHE (0.59) | DHPSEGLN1LMNAKDM4EHTT | |
| SCHEMBL7828943 | 0.72 | ALDH1A1 (0.59) | EGLN1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL5334485 | 0.70 | DHPS (0.45) | DHPSEGLN1LMNAKDM4EHTT | |
| SCHEMBL6385918 | 0.70 | MEN1 (0.46) | DHPSEGLN1LMNAKDM4EHTT | |
| SCHEMBL1774558 | 0.70 | HTR6 (0.49) | LMNAKDM4EHTTALDH1A1HPGD | |
| SCHEMBL23425580 | 0.70 | HTR2A (0.48) | DHPSSTING1EIF4EBP1KDM4EHTR1A | |
| SCHEMBL26703744 | 0.70 | HTR6 (0.62) | KDM4CKDM4EALDH1A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706412-A4 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK CHEMICALS CO LTD (KR) | 2009-03-18 | — | — | EP | disclosed |
| EP-1706412-A1 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK Chemicals, Co., Ltd. (KR) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005063768-A1 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK CHEMICALS, CO., LTD. (KR) | 2005-07-14 | — | — | WO | disclosed |