Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20132172 | 0.78 | HDAC3 (0.50) | TDP2CYP1A2KMT2ACYP2C9CYP3A4 | |
| SCHEMBL999347 | 0.78 | KMT2A (0.61) | TDP2CYP1A2KMT2ACYP3A4GAA | |
| SCHEMBL3892771 | 0.78 | ALDH1A1 (0.52) | TDP2CYP1A2KMT2ACYP3A4MAPT | |
| SCHEMBL6815016 | 0.76 | NAMPT (0.61) | CYP17A1NAMPT | |
| SCHEMBL26785208 | 0.75 | MAPK1 (0.50) | TDP2CYP1A2KMT2ACYP2C9CYP3A4 | |
| SCHEMBL5894005 | 0.75 | CA2 (0.52) | KMT2ACYP3A4GAACYP17A1NAMPT | |
| SCHEMBL281590 | 0.75 | RAB9A (0.59) | KMT2AMAPTALDH1A1MAPK1POLB | |
| SCHEMBL23871058 | 0.74 | MAPK1 (0.49) | TDP2CYP1A2KMT2ACYP2C9CYP3A4 | |
| SCHEMBL28890018 | 0.74 | ACHE (0.49) | TDP2KMT2ACYP3A4FAAHALDH1A1 | |
| SCHEMBL29029431 | 0.74 | HDAC3 (0.56) | MAPTCYP17A1NAMPTMAPK1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |