Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082554 | 0.78 | KCNH3 (0.43) | CNR2PLK1HPGD | |
| SCHEMBL1467336 | 0.76 | LMNA (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL9195780 | 0.76 | PLK1 (0.52) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL1081781 | 0.75 | CNR2 (0.39) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL1075649 | 0.75 | AKR1C2 (0.48) | KDM4EGAAMAPTMGLLPLK1 | |
| SCHEMBL2913206 | 0.74 | HCAR3 (0.48) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL3396257 | 0.74 | KDM4E (0.52) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8715959 | 0.74 | CNR2 (0.58) | CNR2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9194517 | 0.74 | ABL1 (0.47) | KDM4EGLA | |
| SCHEMBL12255222 | 0.74 | POLB (0.44) | CNR2KDM4EALDH1A1GLATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127822-A2 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2009-10-22 | — | — | WO | disclosed |