Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 5/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.70 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16379444 | 0.91 | EYA3 (0.57) | EYA3PTPN1SLC22A12TTRNR1H4 | |
| SCHEMBL5020570 | 0.90 | EYA3 (0.77) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL13890098 | 0.87 | KDM5A (0.62) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL12074771 | 0.87 | SLC22A12 (0.57) | EYA3PTPN1SLC22A12CYP2C9NR1H4 | |
| SCHEMBL14552011 | 0.87 | EYA3 (0.72) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5226741 | 0.87 | EYA3 (0.72) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| Hydrochloric Acid SCHEMBL27860354 | 0.86 | SLC22A12 (0.56) | EYA3PTPN1SLC22A12CYP2C9NR1H4 | |
| SCHEMBL11817673 | 0.86 | EYA3 (0.70) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5224414 | 0.85 | EYA3 (0.69) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL15121391 | 0.85 | EYA3 (0.51) | EYA3PTPN1TTRNR1H4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636670-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2016-06-01 | — | — | EP | disclosed |
| EP-2417099-B1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2388256-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| US-8889734-B2 | Process for the preparation of dronedarone | SANOFI (FR) | 2014-11-18 | — | — | US | disclosed |
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2014-07-24 | — | — | US | disclosed |
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2014-07-24 | — | — | US | disclosed |
| US-8779201-B2 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2014-07-15 | — | — | US | disclosed |
| US-8779201-B2 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2014-07-15 | — | — | US | disclosed |
| US-20130261321-A1 | PROCESS FOR THE PREPARATION OF DRONEDARONE | SANOFI (FR) | 2013-10-03 | — | — | US | disclosed |
| EP-2636670-A1 | Process for preparing benzofurans | Cambrex Karlskoga AB (SE) | 2013-09-11 | — | — | EP | disclosed |
| US-20120122971-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2012-05-17 | — | — | US | disclosed |
| US-20120122971-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2012-05-17 | — | — | US | disclosed |
| US-20120046356-A1 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046356-A1 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2012-02-23 | — | — | US | disclosed |
| EP-2388256-A1 | Process for preparing benzofurans | Cambrex Karlskoga AB (SE) | 2011-11-23 | — | — | EP | disclosed |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| WO-2010116140-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010038029-A1 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
| WO-2009044143-A2 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261321-A1 | PROCESS FOR THE PREPARATION OF DRONEDARONE | CYP2D6, CYP3A4, CYP4B1 | EYA3 4784/4885PTPN1 3879/4885SLC22A12 4074/4885 |
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CYP3A4, CYP1A2, CYP2D6 | EYA3 4536/4885PTPN1 4738/4885SLC22A12 2997/4885 |
| US-20120046356-A1 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS | CYP3A4, DHPS, CYP2D6 | EYA3 3787/4885PTPN1 4560/4885SLC22A12 3774/4885 |
| US-20120122971-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CYP3A4, CYP1A2, CYP4B1 | EYA3 4494/4885PTPN1 4735/4885SLC22A12 2879/4885 |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CYP2F1, CYP3A4, CYP4F3 | EYA3 4548/4885PTPN1 4513/4885SLC22A12 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.