Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 5/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.72 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14552010 | 0.94 | EYA3 (0.62) | EYA3PTPN1SLC22A12TTRNR1H4 | |
| SCHEMBL5020570 | 0.91 | EYA3 (0.77) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5226741 | 0.88 | EYA3 (0.72) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL15488929 | 0.87 | SLC22A12 (0.58) | EYA3PTPN1SLC22A12CYP2C9NR1H4 | |
| SCHEMBL14707711 | 0.87 | KDM5A (0.63) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL11817673 | 0.87 | EYA3 (0.70) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL4567255 | 0.87 | EYA3 (0.70) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL18286467 | 0.86 | NR1H4 (0.57) | NR1H4ESR1PGRCHRM2HTR1A | |
| SCHEMBL25390705 | 0.86 | EYA3 (0.75) | EYA3PTPN1CYP2C9TTRPGR | |
| SCHEMBL5224414 | 0.86 | EYA3 (0.69) | EYA3PTPN1SLC22A12CYP2C9TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512097-B2 | Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives | LEK PHARMACEUTICALS D.D. (SI) | 2016-12-06 | — | — | US | disclosed |
| US-8658808-B2 | Process for the production of dronedarone intermediates | SANOFI (FR) | 2014-02-25 | — | — | US | disclosed |
| US-20130012729-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES | SANOFI (FR) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012729-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES | NNMT, DHPS, NDUFC1 | EYA3 1512/4885PTPN1 4282/4885SLC22A12 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.