Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4567078 | 0.95 | ALDH1A1 (0.50) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL16020394 | 0.93 | ADRA2A (0.48) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL16020427 | 0.93 | HTR2C (0.53) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL14296732 | 0.91 | ADRA2A (0.43) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL13635974 | 0.90 | ALDH1A1 (0.56) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL18025258 | 0.89 | ADRA2A (0.42) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL4570260 | 0.89 | ADRA2A (0.45) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL118152 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL14573478 | 0.87 | ALDH1A1 (0.53) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL875181 | 0.87 | HTR2C (0.62) | ALDH1A1DGKAHTR2CNAAADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872611-B1 | GLYCOL DILEVULINATES AS COUPLING AGENTS IN CLEANING FORMULATIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-08-10 | — | — | EP | claimed |
| US-9840607-B2 | Polyhydroxy ketal ester adducts, methods of manufacture and uses thereof | GFBIOCHEMICALS LIMITED (MT) | 2017-12-12 | — | — | US | disclosed |
| US-9840607-B2 | Polyhydroxy ketal ester adducts, methods of manufacture and uses thereof | GFBIOCHEMICALS LIMITED (MT) | 2017-12-12 | — | — | US | disclosed |
| US-20160237302-A1 | WATERBORNE COMPOSITIONS | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2016-08-18 | — | — | US | disclosed |
| US-20160237302-A1 | WATERBORNE COMPOSITIONS | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2016-08-18 | — | — | US | disclosed |
| US-20160068660-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | GFBIOCHEMICALS LIMITED (MT) | 2016-03-10 | — | — | US | disclosed |
| US-20160068660-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | GFBIOCHEMICALS LIMITED (MT) | 2016-03-10 | — | — | US | disclosed |
| US-9221741-B2 | Ketocarboxylic acids, ketocarboxylic esters, methods of manufacture and uses thereof | SEGETIS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221741-B2 | Ketocarboxylic acids, ketocarboxylic esters, methods of manufacture and uses thereof | SEGETIS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-9187598-B2 | Polyhydroxy ketal ester adducts, methods of manufacture and uses thereof | SEGETIS, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| US-20130296601-A1 | KETOCARBOXYLIC ACIDS, KETOCARBOXYLIC ESTERS, METHODS OF MANUFACTURE AND USES THEREOF | GFBIOCHEMICALS LIMITED (MT) | 2013-11-07 | — | — | US | disclosed |
| US-8507718-B2 | Ketocarboxylic acids, methods of manufacture and uses thereof | SEGETIS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507718-B2 | Ketocarboxylic acids, methods of manufacture and uses thereof | SEGETIS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| WO-2012065116-A2 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | SEGETIS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20120123147-A1 | KETOCARBOXYLIC ACIDS, METHODS OF MANUFACTURE AND USES THEREOF | SEGETIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120121911-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | SEGETIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120123147-A1 | KETOCARBOXYLIC ACIDS, METHODS OF MANUFACTURE AND USES THEREOF | SEGETIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120121911-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | SEGETIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| EP-2272820-A1 | COMPOUND | FUJIFILM Corporation (JP) | 2011-01-12 | — | — | EP | disclosed |
| EP-2267106-A1 | COMPOSITION AND METHOD FOR FORMING COATING FILM | FUJIFILM Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068660-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | ALKBH3, PHYKPL, KYAT1 | ALDH1A1 1068/4885ADRA2A 3820/4885ADRA1A 3942/4885 |
| US-20120123147-A1 | KETOCARBOXYLIC ACIDS, METHODS OF MANUFACTURE AND USES THEREOF | PHYKPL, HACL2, MCCC2 | ALDH1A1 1223/4885ADRA2A 4634/4885ADRA1A 4734/4885 |
| US-20120121911-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | ALKBH3, PHYKPL, KYAT1 | ALDH1A1 1068/4885ADRA2A 3820/4885ADRA1A 3942/4885 |
| US-20130296601-A1 | KETOCARBOXYLIC ACIDS, KETOCARBOXYLIC ESTERS, METHODS OF MANUFACTURE AND USES THEREOF | PHYKPL, HACL2, MCCC2 | ALDH1A1 1119/4885ADRA2A 4493/4885ADRA1A 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.