Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879118 | 0.93 | ADRA2A (0.48) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL16020457 | 0.93 | ADRA2A (0.48) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL16020410 | 0.93 | ADRA2A (0.48) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL4570263 | 0.93 | ADRA2A (0.48) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL14573478 | 0.92 | ALDH1A1 (0.53) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL756978 | 0.91 | ADRA2A (0.46) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL16285472 | 0.91 | LMNA (0.64) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL4567078 | 0.90 | ALDH1A1 (0.50) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL4567262 | 0.90 | ALDH1A1 (0.50) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL4465312 | 0.89 | ADRA2A (0.54) | ALDH1A1ADRA2AADRA1AMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160237302-A1 | WATERBORNE COMPOSITIONS | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2016-08-18 | — | — | US | disclosed |
| US-20160237302-A1 | WATERBORNE COMPOSITIONS | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2016-08-18 | — | — | US | disclosed |
| WO-2015038012-A1 | WATERBORNE COMPOSITIONS | VICTORIA LINK LIMITED (NZ) | 2015-03-19 | — | — | WO | disclosed |
| US-20130030139-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-01-31 | — | — | US | disclosed |
| US-8303937-B2 | Dendritic polymers and magnetic resonance imaging contrast agent employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-11-06 | — | — | US | disclosed |
| US-20090169481-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169481-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | DCLK1, MSR1, S1PR3 | ALDH1A1 4783/4885ADRA2A 3747/4885ADRA1A 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.