SCHEMBL4567339

SCHEMBL4567339

Cc1c(O)cc(C(C)(C)CCCC(C)(C)C)cc1O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 16/20 0.46
CNR2 P34972 16/20 0.46
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838141 0.81 CNR1 (0.44) CNR1CNR2ACHE
SCHEMBL31545653 0.81 CNR1 (0.44) CNR1CNR2
SCHEMBL31545049 0.81 ESR1 (0.36) CNR1CNR2ACHE
SCHEMBL4567338 0.81 CNR2 (0.44) CNR1CNR2
SCHEMBL13825870 0.73 CNR2 (0.44) CNR1CNR2
SCHEMBL28125325 0.72 SHBG (0.67) CNR1CNR2
SCHEMBL4570710 0.71 CNR1 (0.36) CNR1CNR2
SCHEMBL4567341 0.70 CNR1 (0.35) CNR1CNR2ACHE
SCHEMBL31545819 0.70 RIPK1 (0.42) ACHE
SCHEMBL9744092 0.69 GABRA1 (0.55) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9173867-B2 Treatment of immune dysregulation using cannabinoid derivatives IMMUGEN PHARMACEUTICALS, INC. (US) 2015-11-03 US disclosed
US-9173867-B2 Treatment of immune dysregulation using cannabinoid derivatives IMMUGEN PHARMACEUTICALS, INC. (US) 2015-11-03 US disclosed
US-20140066497-A1 TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES IMMUGEN PHARMACEUTICALS, INC. 2014-03-06 US disclosed
US-20140066497-A1 TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES IMMUGEN PHARMACEUTICALS, INC. 2014-03-06 US disclosed
US-8586767-B2 Method for treatment of HIV and diseases of immune dysregulation TRAVIS CRAIG RICK (US) 2013-11-19 US disclosed
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives TRAVIS CRAIG RICK (US) 2012-11-15 US disclosed
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives TRAVIS CRAIG RICK (US) 2012-11-15 US disclosed
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation TRAVIS CRAIG RICK (US) 2012-05-17 US disclosed
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation TRAVIS CRAIG RICK (US) 2012-05-17 US disclosed
US-20080108647-A1 Treatment of HIV and diseases of immune dysregulation TRAVIS CRAIG R 2008-05-08 US disclosed
US-20080108647-A1 Treatment of HIV and diseases of immune dysregulation TRAVIS CRAIG R 2008-05-08 US disclosed
US-20070179135-A1 Cannabinoid derivatives TRAVIS CRAIG R 2007-08-02 US disclosed
US-20070179135-A1 Cannabinoid derivatives TRAVIS CRAIG R 2007-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140066497-A1 TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES CNR2, CNR1, GPR18 CNR1 2/4885CNR2 1/4885ACHE 2132/4885
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives CNR2, CNR1, GPR18 CNR1 2/4885CNR2 1/4885ACHE 2132/4885
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation CNR2, CNR1, ICOS CNR1 2/4885CNR2 1/4885ACHE 938/4885
US-20070179135-A1 Cannabinoid derivatives CNR2, CNR1, GPR18 CNR1 2/4885CNR2 1/4885ACHE 612/4885
US-20080108647-A1 Treatment of HIV and diseases of immune dysregulation CNR1, CNR2, ICOS CNR1 1/4885CNR2 2/4885ACHE 1939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.