SCHEMBL6838141

SCHEMBL6838141

Cc1c(O)cc(C(C)(C)CCCC(C)C)cc1O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 13/20 0.44
CNR2 P34972 12/20 0.44
AKT1 P31749 3/20 0.39
PDPK1 O15530 1/20 0.39
PHLPP1 O60346 1/20 0.39
ILK Q13418 1/20 0.39
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3694612 0.81 CNR2 (0.42) CNR1CNR2
SCHEMBL4567339 0.81 CNR1 (0.46) CNR1CNR2ACHE
SCHEMBL3701630 0.75 PKM (0.47) CNR1CNR2
SCHEMBL25230502 0.74 SHBG (0.52) CNR1CNR2
SCHEMBL3705499 0.74 CNR2 (0.44) CNR1CNR2
SCHEMBL3693693 0.73 CNR2 (0.45) CNR1CNR2
SCHEMBL27602008 0.71 CNR2 (0.48) CNR1CNR2
SCHEMBL6716285 0.71 CNR2 (0.43) CNR1CNR2ACHE
SCHEMBL17430879 0.70 ALOX15 (0.45)
SCHEMBL4567343 0.70 ACHE (0.31) AKT1PDPK1PHLPP1ILKACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040138315-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation IMMUGEN PHARMACEUTICALS, INC. (US) 2004-07-15 US claimed
WO-2002026224-A9 METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION IMMUGEN PHARMACEUTICALS INC (US) 2003-02-20 WO claimed
US-20020137802-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation IMMUGEN PHARMACEUTICALS, INC. 2002-09-26 US claimed
WO-2002026224-A2 METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION IMMUGEN PHARMACEUTICALS, INC. (US) 2002-04-04 WO claimed
CN-1652766-A Topical formulations of resorcinol and cannabinoids and methods of administration thereof IMMUGEN PHARMACEUTICALS INC (US) 2005-08-10 CN disclosed
US-20040138315-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation IMMUGEN PHARMACEUTICALS, INC. (US) 2004-07-15 US disclosed
WO-2004016254-A2 CONTRACEPTIVE METHODS AND FORMULATIONS IMMUGEN PHARMACEUTICALS, INC. (US) 2004-02-26 WO disclosed
US-20030232101-A1 Topical formulations of resorcinols and cannibinoids and methods of use IMMUGEN PHARMACEUTICALS, INC. 2003-12-18 US disclosed
WO-2003080043-A1 TOPICAL FORMULATIONS OF RESORCINOLS AND CANNIBINOIDS AND METHODS OF USE IMMUGEN PHARMACEUTICALS, INC. (US) 2003-10-02 WO disclosed
WO-2002026224-A9 METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION IMMUGEN PHARMACEUTICALS INC (US) 2003-02-20 WO disclosed
US-20020137802-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation IMMUGEN PHARMACEUTICALS, INC. 2002-09-26 US disclosed
WO-2002026224-A2 METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION IMMUGEN PHARMACEUTICALS, INC. (US) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020137802-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation PTGS1, PTGIS, PTGES CNR1 5/4885CNR2 9/4885AKT1 1456/4885
US-20030232101-A1 Topical formulations of resorcinols and cannibinoids and methods of use CNR2, CNR1, CXCL8 CNR1 2/4885CNR2 1/4885AKT1 771/4885
US-20040138315-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation PTGS1, PTGIS, PTGES CNR1 5/4885CNR2 9/4885AKT1 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.