Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532060 | 0.91 | PTAFR (0.35) | ALDH1A1GLACA1CA2CA4 | |
| SCHEMBL4539391 | 0.91 | PTAFR (0.35) | ALDH1A1GLACA1CA2CA4 | |
| SCHEMBL4529772 | 0.91 | PTAFR (0.35) | ALDH1A1GLACA1CA2CA4 | |
| SCHEMBL18928155 | 0.76 | PTAFR (0.36) | CA1CA2CA4CA7 | |
| SCHEMBL30137694 | 0.71 | PTAFR (0.41) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL1655758 | 0.71 | PTAFR (0.41) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL12362314 | 0.70 | HDAC8 (0.39) | CA1CA2CA4CA7 | |
| SCHEMBL4569733 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL17732339 | 0.70 | P2RX7 (0.34) | ALDH1A1TP53MAPTHPGDTSHR | |
| SCHEMBL1658299 | 0.69 | KDM4E (0.41) | ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638043-A1 | ARYLAMINOALCOHOL-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINOLINES | Bayer Intellectual Property GmbH (DE) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062743-A1 | ARYLAMINOALCOHOL-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-18 | — | — | WO | disclosed |