Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL401293 | 0.85 | CYP1A2 (0.48) | ALDH1A1CYP1A2KMT2AKDM4ERECQL | |
| SCHEMBL28506559 | 0.83 | CYP1A2 (0.47) | ALDH1A1CYP1A2KMT2AKDM4ERECQL | |
| SCHEMBL3109540 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP1A2KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL21603204 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP1A2KMT2AMEN1HTT | |
| SCHEMBL891790 | 0.77 | — | — | |
| SCHEMBL29450819 | 0.76 | PDE2A (0.55) | ALDH1A1CYP1A2KMT2AMEN1HTT | |
| SCHEMBL7052100 | 0.76 | PDE2A (0.55) | ALDH1A1CYP1A2KMT2AMEN1HTT | |
| SCHEMBL2633440 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CYP1A2KDM4ERECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2845698 | 0.75 | POLB (0.46) | ALDH1A1KMT2AMEN1HTTKDM4E | |
| SCHEMBL423189 | 0.74 | LMNA (0.52) | ALDH1A1CYP1A2KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447042-B2 | Endoparasite control agent | THE UNIVERSITY OF TOKYO (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20140088157-A1 | ENDOPARASITE CONTROL AGENT | NIHON NOHYAKU CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| US-8378114-B2 | N-2-(hetero)arylethylcarboxamide derivative, and pest-controlling agent comprising the same | NIHON NOHYAKU CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8168638-B2 | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | NIHON NOHYAKU CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20110136831-A1 | N-2-(Hetero)Arylethylcarboxamide Derivative, and Pest-Controlling Agent Comprising the Same | NIHON NOHYAKU CO., LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
| US-20090233934-A1 | Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same | NIHON NOHYAKU CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-4113860-A | O-alkyl-O-[4-alkylpyrimidin(2)yl]-(thiono)-(thiol) phosphoric (phosphonic) acid esters and insecticidal, acaricidal and nematocidal compositions containing them | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088157-A1 | ENDOPARASITE CONTROL AGENT | SI, NAAA, STOM | ALDH1A1 3491/4885CYP1A2 1150/4885KMT2A 930/4885 |
| US-20110136831-A1 | N-2-(Hetero)Arylethylcarboxamide Derivative, and Pest-Controlling Agent Comprising the Same | H1-2, CNPY2, H1-0 | ALDH1A1 4470/4885CYP1A2 958/4885KMT2A 45/4885 |
| US-20090233934-A1 | Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same | CBR3, CNPY2, AADAC | ALDH1A1 3219/4885CYP1A2 1212/4885KMT2A 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.