SCHEMBL401293

SCHEMBL401293

COc1cc(OC)nc(O)n1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.42
RECQL P46063 1/20 0.41
PDE2A O00408 1/20 0.39
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28506559 0.97 CYP1A2 (0.47) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL3109540 0.87 ALDH1A1 (0.42) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL4570474 0.85 ALDH1A1 (0.46) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL2633440 0.84 ALDH1A1 (0.44) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL16329868 0.80 ALDH1A1 (0.37) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL6335607 0.79 L3MBTL1 (0.37) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL6337444 0.79 PDGFRB (0.44) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL28047971 0.78 ALDH1A1 (0.52) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL6806147 0.77 LMNA (0.53) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL13729689 0.77 NNMT (0.50) CYP1A2LMNASMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100210467-A1 AGENT FOR IMPROVING SUGARCANE BRIX AND METHOD OF PROMOTING SUGARCANE RIPENING USING THE SAME KUMIAI CHEMICAL INDUSTRY CO., LTD. 2010-08-19 US claimed
EP-0507962-B1 PICOLINIC ACID DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 2001-06-13 EP claimed
EP-0671880-A1 SELECTIVE HERBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1995-09-20 EP claimed
US-5391537-A Picolinic acid derivative, and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-02-21 US claimed
WO-1994000987-A2 SELECTIVE HERBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1994-01-20 WO claimed
EP-0507962-A1 PICOLINIC ACID DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-10-14 EP claimed
CN-110959138-B Resist material DIC株式会社 2023-06-30 CN disclosed
US-11487204-B2 Resist material DIC CORPORATION (JP) 2022-11-01 US disclosed
EP-3153023-B1 BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE TAKEDA PHARMACEUTICALS CO (JP) 2022-03-16 EP disclosed
US-20210253566-A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF ANGION BIOMEDICA CORP. 2021-08-19 US disclosed
CN-112961149-A Cytochrome P450 inhibitors and uses thereof 安吉恩生物医药公司 2021-06-15 CN disclosed
US-20210171515-A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF ANGION BIOMEDICA CORP. 2021-06-10 US disclosed
EP-3180335-B1 CYTOCHROME P450 INHIBITORS AND USES THEREOF ANGION BIOMEDICA CORP (US) 2021-05-05 EP disclosed
US-5202329-A Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient MITSUI TOATSU CHEMICALS INC. (JP) 1993-04-13 US disclosed
EP-0532761-A1 PYRIDINE DERIVATIVE, PRODUCTION THEREOF, HERBICIDE AND METHOD OF WEEDING KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-03-24 EP disclosed
EP-0507962-A1 PICOLINIC ACID DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-10-14 EP disclosed
EP-0497371-A1 Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-08-05 EP disclosed
US-5087289-A ALKANOIC ACID DERIVATIVES AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-02-11 US disclosed
US-4968340-A PREEMERGENCE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-11-06 US disclosed
EP-0347811-A1 Alkanoic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171515-A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF CYP7A1, CYP2E1, CYP11B1 CYP1A2 4/4885LMNA 2070/4885SMN1; SMN2 3698/4885
US-20210253566-A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF CYP7A1, CYP2E1, CYP1A2 CYP1A2 3/4885LMNA 2143/4885SMN1; SMN2 3732/4885
US-11487204-B2 Resist material FLNA, AFF1, RXRA CYP1A2 1595/4885LMNA 985/4885SMN1; SMN2 2194/4885
US-20100210467-A1 AGENT FOR IMPROVING SUGARCANE BRIX AND METHOD OF PROMOTING SUGARCANE RIPENING USING THE SAME BRIX1, MGAM, MGAM2 CYP1A2 3682/4885LMNA 3335/4885SMN1; SMN2 1337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.