Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | CASP3 | P42574 | 1/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.75 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.68 |
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62862 | 1.00 | KMT2A (0.75) | KMT2AMEN1MAPTCASP3TRPV1 | |
| Hydrochloric Acid SCHEMBL28579442 | 0.98 | KMT2A (0.73) | KMT2AMEN1MAPTCASP3TRPV1 | |
| SCHEMBL7365076 | 0.94 | KMT2A (0.69) | KMT2AMEN1MAPTCASP3TRPV1 | |
| Propene SCHEMBL27901997 | 0.91 | KMT2A (0.65) | KMT2AMEN1MAPTCASP3TRPV1 | |
| Benzocaine SCHEMBL8185923 | 0.91 | LMNA (0.83) | KMT2AMEN1MAPTCASP3TRPV1 | |
| SCHEMBL7767342 | 0.91 | KMT2A (0.65) | KMT2AMEN1MAPTCASP3TRPV1 | |
| SCHEMBL3983761 | 0.89 | CA1 (0.70) | KMT2AMEN1MAPTCASP3TRPV1 | |
| Alcohol SCHEMBL27327774 | 0.89 | CA1 (0.76) | KMT2AMEN1MAPTCASP3TRPV1 | |
| SCHEMBL87450 | 0.89 | CA1 (0.83) | KMT2AMEN1MAPTCASP3TRPV1 | |
| SCHEMBL4049821 | 0.88 | KMT2A (0.61) | KMT2AMEN1MAPTCASP3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674101-B2 | Nucleophilic fluorination of aromatic compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120107175-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110178302-A1 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| US-7919579-B2 | Imaging and therapeutic targeting of prostate and bladder tissues | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-04-05 | — | — | US | disclosed |
| US-20090123381-A1 | IMAGING AND THERAPEUTIC TARGETING OF PROSTATE AND BLADDER TISSUES | US ARMY, SECRETARY OF THE ARMY | 2009-05-14 | — | — | US | disclosed |
| US-20070276231-A1 | Positron Emission Tomography Imaging Method | PURDUE RESEARCH FOUNDATION | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178302-A1 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | SLC18A2, AFF4, SLC6A19 | KMT2A 143/4885MEN1 1572/4885MAPT 2189/4885 |
| US-20090123381-A1 | IMAGING AND THERAPEUTIC TARGETING OF PROSTATE AND BLADDER TISSUES | ADM2, DAB2IP, ARG2 | KMT2A 2593/4885MEN1 433/4885MAPT 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.