SCHEMBL457203

SCHEMBL457203

Fc1cc(F)c(N=C=S)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
MIF P14174 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14683171 0.85
SCHEMBL17650908 0.85 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL17650996 0.85 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL23240165 0.81 GABRA1 (0.32) GABRA1GABRB2MIF
SCHEMBL25573712 0.81 GABRA1 (0.36) GABRA1GABRB2MIF
SCHEMBL11555693 0.81 GABRA1 (0.36) GABRA1GABRB2MIF
SCHEMBL28374773 0.81 TAAR1 (0.35) GABRA1GABRB2MIF
SCHEMBL3612484 0.80 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL17650044 0.78 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL2824472 0.77 MIF (0.44) MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084759-A1 FLUORESCENT DYE OIL TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2025-03-13 US claimed
CN-115411362-A Electrolyte for lithium ion battery, lithium ion battery and preparation method thereof 江苏海四达电源有限公司 2022-11-29 CN claimed
US-20250084759-A1 FLUORESCENT DYE OIL TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2025-03-13 US disclosed
EP-4139286-B1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION BAYER AG (DE) 2025-02-26 EP disclosed
US-12215108-B2 Development of potential antidotes for arsenicals SOUTHERN RESEARCH INSTITUTE (US) 2025-02-04 US disclosed
US-12188350-B2 Fluorescent dye oil tracer compositions SAUDI ARABIAN OIL COMPANY (SA) 2025-01-07 US disclosed
CN-115557908-B Triazine derivative containing sulfur connecting bond, and synthesis method and application thereof 九江学院 2024-10-15 CN disclosed
US-11964953-B2 Substituted aminothiazoles as DGKzeta inhibitors for immune activation BAYER AKTIENGESELLSCHAFT (DE) 2024-04-23 US disclosed
EP-3822274-B1 SYNTHETIC INTERMEDIATES USEFUL FOR PREPARING SUBSTITUTED AMINOPURINE COMPOUNDS SIGNAL PHARM LLC (US) 2024-03-06 EP disclosed
US-20230399942-A1 FLUORESCENT DYE OIL TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-12-14 US disclosed
US-20230399942-A1 FLUORESCENT DYE OIL TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-12-14 US disclosed
WO-2006122769-A2 SUBSTITUTED SPIRO COMPOUNDS AND THEIR USE FOR PRODUCING PAIN-RELIEF DRUGS Grünenthal GmbH (DE) 2006-11-23 WO disclosed
WO-2006122770-A1 SUBSTITUTED SPIRO COMPOUNDS AND THEIR USE FOR PRODUCING PAIN-RELIEF MEDICAMENTS Grünenthal GmbH (DE) 2006-11-23 WO disclosed
US-5914343-A TREATING CANCER, RESTENOSIS, ATHEROSCLEROSIS, HOST VERSUS GRAFT REJECTION SUGEN, INC. (US) 1999-06-22 US disclosed
US-5760066-A AIDS, ATHEROSCLEROSIS, CANCER SUGEN, INC. (US) 1998-06-02 US disclosed
WO-1996033179-A1 THIOAMIDES DERIVATES AND THEIR USE AS INHIBITORS OF HYPER-PROLIFERATIVE CELL GROWTH SUGEN, INC. (US) 1996-10-24 WO disclosed
EP-0227088-B1 ISOXAZOLO-NAPHTHYRIDINE, ISOXAZOLO QUINOLINE, ISOTHIAZOLONAPHTHYRIDINE, AND ISOTHIAZOLOQUINOLINE DERIVATIVES ABBOTT LABORATORIES (US) 1991-08-07 EP disclosed
US-4767762-A Tricyclic quinoline and naphthyride antibacterials ABBOTT LABORATORIES (US) 1988-08-30 US disclosed
EP-0227088-A1 Isoxazolo-naphthyridine, isoxazolo quinoline, isothiazolonaphthyridine, and isothiazoloquinoline derivatives ABBOTT LABORATORIES (US) 1987-07-01 EP disclosed
US-4138242-A Novel 2-aryl-2,3,5,6,7,8-hexahydro-3-thioxoimidazo-[1,5-a-]pyridin-1(BaH)-ones as herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215108-B2 Development of potential antidotes for arsenicals RIPK1, RIPK3, RIPK4 GABRA1 4145/4885GABRB2 3581/4885MIF 4647/4885
US-11964953-B2 Substituted aminothiazoles as DGKzeta inhibitors for immune activation DGKZ, DGKA, DGKG GABRA1 2836/4885GABRB2 2757/4885MIF 3660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.