SCHEMBL4572227

SCHEMBL4572227

CC(C)(C)CC(COC(C)(C)C)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16577201 1.00 MAPK1 (0.41) MAPK1
SCHEMBL755226 0.85 MAPK1 (0.48) MAPK1
SCHEMBL13759439 0.85
SCHEMBL19543102 0.82
SCHEMBL19543111 0.81 MAPK1 (0.34) MAPK1
SCHEMBL19543105 0.78 MAPK1 (0.32) MAPK1
SCHEMBL17085245 0.78 MAPK1 (0.42) MAPK1
SCHEMBL15760607 0.78 MAPK1 (0.42) MAPK1
SCHEMBL16368826 0.78 MAPK1 (0.42) MAPK1
SCHEMBL20995928 0.78 MAPK1 (0.42) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3826985-B1 DENDRIMER-TYPE COMPOUNDS, METHODS FOR PRODUCING SAME, AND USES THEREOF UNIV REIMS CHAMPAGNE ARDENNE (FR) 2022-05-04 EP disclosed
WO-2020021034-A1 DENDRIMER-TYPE COMPOUNDS, METHODS FOR PRODUCING SAME, AND USES THEREOF UNIVERSITE DE REIMS CHAMPAGNE ARDENNE (FR) 2020-01-30 WO disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
US-9593204-B2 Branched polymeric emulsifiers LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-03-14 US disclosed
US-20170049765-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMMAVE THERAPEUTICS SA (CH) 2017-02-23 US disclosed
US-9453037-B2 Methylphenidate-prodrugs, processes of making and using the same KEMPHARM, INC (US) 2016-09-27 US disclosed
US-20150266911-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMMAVE THERAPEUTICS SA (CH) 2015-09-24 US disclosed
US-9079928-B2 Methylphenidate-oxoacid conjugates, processes of making and using the same KEMPHARM, INC. (US) 2015-07-14 US disclosed
US-20140243291-A1 METHYLPHENIDATE-OXOACID CONJUGATES, PROCESSES OF MAKING AND USING THE SAME COMMAVE THERAPEUTICS SA (CH) 2014-08-28 US disclosed
US-8211850-B2 Polyglyceryl compounds and compositions JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-07-03 US disclosed
US-20120123104-A1 POLYGLYCERYL COMPOUNDS AND COMPOSITIONS KENVUE BRANDS LLC 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120123104-A1 POLYGLYCERYL COMPOUNDS AND COMPOSITIONS PHOSPHO1, SGMS1, SGMS2 MAPK1 2727/4885
US-20140243291-A1 METHYLPHENIDATE-OXOACID CONJUGATES, PROCESSES OF MAKING AND USING THE SAME COMT, PNMT, SLC6A3 MAPK1 2426/4885
US-20170049765-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMT, TPMT, PNMT MAPK1 2306/4885
US-20150266911-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMT, TPMT, PNMT MAPK1 2306/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 MAPK1 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.