SCHEMBL4572941 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CCR1	P32246	2/20	0.44

▸	CTSB	P07858	2/20	0.42

▸	CTSS	P25774	2/20	0.42

▸	CTSK	P43235	2/20	0.42

▸	FAAH	O00519	4/20	0.42

▸	CHRM4	P08173	3/20	0.42

▸	SUV39H2	Q9H5I1	3/20	0.41

▸	NR1H2	P55055	6/20	0.40

▸	NR1H3	Q13133	6/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4573183	0.90	CCR1 (0.46)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL4573134	0.86	SUV39H2 (0.53)	CCR1FAAHSUV39H2NR1H2NR1H3
SCHEMBL4574325	0.86	SUV39H2 (0.53)	CCR1FAAHSUV39H2NR1H2NR1H3
SCHEMBL4585200	0.85	CTSB (0.54)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL4573207	0.81	SUV39H2 (0.45)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL19096995	0.80	CTSB (0.46)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL19096994	0.80	CTSB (0.46)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL19096985	0.80	CTSB (0.46)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL4573197	0.79	CTSB (0.46)	CCR1CTSBCTSSCTSKFAAH
SCHEMBL4573031	0.76	FAAH (0.46)	CCR1CTSBCTSSCTSKFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009001127-A1	CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS	ASTRAZENECA AB (SE)	2008-12-31	—	—	WO	disclosed