Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572941 | 0.90 | CCR1 (0.44) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL4585200 | 0.88 | CTSB (0.54) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL4584889 | 0.85 | SUV39H2 (0.53) | CCR1FAAHSUV39H2 | |
| SCHEMBL8112263 | 0.85 | SUV39H2 (0.53) | CCR1FAAHSUV39H2 | |
| SCHEMBL4573207 | 0.83 | SUV39H2 (0.45) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL19096994 | 0.82 | CTSB (0.46) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL19096995 | 0.82 | CTSB (0.46) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL19096985 | 0.82 | CTSB (0.46) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL4573197 | 0.82 | CTSB (0.46) | CCR1FAAHCTSBCTSSCTSK | |
| SCHEMBL4573031 | 0.79 | FAAH (0.46) | CCR1FAAHCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |