Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23375946 | 0.84 | ALDH1A1 (0.52) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL6434819 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNASAE1UBA2MEN1 | |
| SCHEMBL469386 | 0.80 | ALDH1A1 (0.72) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL3560236 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7533924 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL838486 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNASAE1UBA2ADH1B | |
| SCHEMBL4573269 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL6664376 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL14679247 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8866777 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
| WO-2008077651-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | PNPO, DPYD, PNP | ALDH1A1 1142/4885LMNA 879/4885SAE1 4262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.