Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434819 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL469386 | 0.80 | ALDH1A1 (0.72) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL23375946 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL6664376 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL14679247 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNACA1CA2MEN1 | |
| SCHEMBL838486 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL4573264 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAADH1BADH1CADH1A | |
| SCHEMBL4573269 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNACA1CA2 | |
| SCHEMBL3560236 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8866777 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-0145304-B1 | TETRAHYDRO-BETA-CARBOLINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Tanabe Seiyaku Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0128021-B1 | TETRAHYDRO-BETA-CARBOLINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Tanabe Seiyaku Co., Ltd. (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4628057-A | Tetrahydro-β-carboline derivatives and treatment of liver diseases | TANABE SEIYAKU CO., LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
| US-4612317-A | Tetrahydro-β-carboline dithioic acid derivatives and treatment of liver diseases | TANABE SEIYAKU CO., LTD. (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0145304-A1 | Tetrahydro-beta-carboline derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0128021-A1 | Tetrahydro-beta-carboline derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1984-12-12 | — | — | EP | disclosed |