Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678540 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LOXL2CA1CA2CA12 | |
| SCHEMBL6434819 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL2386465 | 0.81 | BLM (0.47) | ALDH1A1LOXL2CA1CA2CA12 | |
| SCHEMBL469386 | 0.80 | ALDH1A1 (0.72) | ALDH1A1LMNAMAPT | |
| SCHEMBL4598099 | 0.79 | HTR6 (0.50) | ALDH1A1LOXL2 | |
| SCHEMBL23375946 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNA | |
| SCHEMBL3560236 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHDAC3HDAC6MAPT | |
| SCHEMBL4573264 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL6664376 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL7533924 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
| WO-2008077651-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-104961644-A | Method used for preparing N-aryl amide compound | UNIV SHANGHAI JIAOTONG | 2015-10-07 | — | — | CN | disclosed |
| CN-100351228-C | Hydroxamic acid derivatives and the method for preparing thereof | AMOREPACIFIC CORP (KR) | 2007-11-28 | — | — | CN | disclosed |
| CN-1839115-A | Hydroxamic acid derivatives and preparation method thereof | AMOREPACIFIC CORP (KR) | 2006-09-27 | — | — | CN | disclosed |
| CN-1239474-C | Process for preparing uretdione polyisocyanates with improved monomer stability | BAYER AG (DE) | 2006-02-01 | — | — | CN | disclosed |
| CN-1506355-A | Diphenyl benzimidazole compound containing sulfonyl group and its prepn process, medicinal composition and use | 中国医学科学院药物研究所 | 2004-06-23 | — | — | CN | disclosed |
| CN-1334264-A | Process for preparing uretdione polyisocyanates with improved monomer stability | BAYER AG (DE) | 2002-02-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | PNPO, DPYD, PNP | ALDH1A1 1142/4885HRH3 207/4885LOXL2 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.