Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 5/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596716 | 0.90 | AGTR2 (0.41) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4590621 | 0.90 | AGTR2 (0.41) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4590389 | 0.85 | RORC (0.37) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4573810 | 0.85 | RIPK1 (0.42) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4574349 | 0.75 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL14013955 | 0.75 | GRIN2D (0.37) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL27030606 | 0.75 | ALDH1A1 (0.48) | MAP4K4RIPK1ALDH1A1 | |
| SCHEMBL29586935 | 0.73 | SCN3A (0.49) | RIPK1 | |
| SCHEMBL14013950 | 0.72 | NR1H2 (0.45) | DPP4RIPK1ALDH1A1CHRM4 | |
| SCHEMBL21229957 | 0.71 | PTGDR2 (0.45) | RORCRIPK1KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |