Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 9/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591026 | 1.00 | RIPK1 (0.43) | RIPK1CHRM1CHRM2ALDH1A1DPP4 | |
| SCHEMBL4591030 | 1.00 | RIPK1 (0.43) | RIPK1CHRM1CHRM2ALDH1A1DPP4 | |
| SCHEMBL14013369 | 0.78 | CFD (0.37) | RIPK1 | |
| SCHEMBL14013278 | 0.78 | CFD (0.37) | RIPK1 | |
| SCHEMBL4574349 | 0.77 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL20818283 | 0.73 | ALDH1A1 (0.48) | CHRM1ALDH1A1 | |
| SCHEMBL3322121 | 0.72 | CHRM1 (0.55) | CHRM1ALDH1A1 | |
| SCHEMBL4575085 | 0.71 | RIPK1 (0.38) | RIPK1DPP4 | |
| SCHEMBL4574098 | 0.71 | RIPK1 (0.38) | RIPK1DPP4 | |
| SCHEMBL8033959 | 0.70 | CHRM1 (0.54) | CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |