Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 3/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574119 | 0.81 | RIPK1 (0.36) | RORCALDH1A1CHRM4 | |
| SCHEMBL3965653 | 0.77 | ALDH1A1 (0.50) | JAK2JAK3GAARORCALDH1A1 | |
| SCHEMBL14708215 | 0.77 | JAK2 (0.52) | JAK2JAK3GAAJAK1TYK2 | |
| SCHEMBL4574387 | 0.76 | JAK2 (0.44) | JAK2JAK3GAAJAK1TYK2 | |
| SCHEMBL11742027 | 0.73 | ACHE (0.53) | ALDH1A1POLB | |
| SCHEMBL16477300 | 0.72 | JAK2 (0.48) | JAK2JAK3GAAJAK1TYK2 | |
| SCHEMBL6803849 | 0.72 | ALDH1A1 (0.70) | GAAALDH1A1ARCYP2A13POLB | |
| SCHEMBL6384809 | 0.71 | ALDH1A1 (0.50) | GAAALDH1A1ARCYP2A13POLB | |
| SCHEMBL30341108 | 0.71 | ALDH1A1 (0.73) | GAAALDH1A1ARCYP2A13POLB | |
| SCHEMBL6943859 | 0.69 | ATM (0.49) | JAK2JAK3GAARORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |