Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598244 | 0.81 | CHRM2 (0.54) | BCHECHRM2MAPK14SCN8ACETP | |
| SCHEMBL9902980 | 0.79 | CHRM2 (0.50) | BCHECHRM2MAPK14SCN8ACETP | |
| SCHEMBL9882943 | 0.77 | SIGMAR1 (0.49) | BCHEKDM4ECHRM2MAPK14SCN8A | |
| Trifluoroacetic Acid SCHEMBL947858 | 0.77 | DRD2 (0.50) | BCHEKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL20776850 | 0.76 | CARM1 (0.51) | BCHEKDM4ESMN1; SMN2CHRM2MEN1 | |
| SCHEMBL14966127 | 0.76 | USP28 (0.62) | BCHEKDM4ECHRM2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8514570 | 0.76 | SIGMAR1 (0.48) | BCHEKDM4ECHRM2MAPK14SCN8A | |
| Trifluoroacetic Acid SCHEMBL951044 | 0.76 | DRD2 (0.49) | BCHEKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9882938 | 0.75 | SIGMAR1 (0.53) | BCHEKDM4ECHRM2MEN1KMT2A | |
| SCHEMBL15341674 | 0.75 | MAOA (0.62) | BCHEKDM4ECHRM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |