Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23923900 | 0.65 | GAA (0.39) | MAPK1 | |
| SCHEMBL30317842 | 0.64 | SLC9A1 (0.36) | MAPK1PTGS2 | |
| SCHEMBL4575448 | 0.64 | ALDH1A1 (0.35) | PTGS2 | |
| SCHEMBL5756302 | 0.59 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL2117133 | 0.58 | CA1 (0.48) | MAPK1PTGS2 | |
| SCHEMBL4575203 | 0.58 | — | — | |
| SCHEMBL1940207 | 0.58 | LMNA (0.38) | L3MBTL1PTGS2 | |
| SCHEMBL24876001 | 0.56 | GRIN2D (0.64) | — | |
| SCHEMBL2220389 | 0.56 | SMN1; SMN2 (0.35) | PTGS2 | |
| SCHEMBL15478488 | 0.56 | RAPGEF4 (0.52) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | claimed |
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | disclosed |