Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336609 | 0.74 | TDP1 (0.78) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL27572770 | 0.73 | KDM4E (0.49) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL27571353 | 0.73 | MAPT (0.52) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL27640819 | 0.72 | MAPK8 (0.52) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL19302733 | 0.72 | MAPT (0.48) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL27772170 | 0.71 | CREBBP (0.45) | TDP1KMT2AMEN1LMNAMAPT | |
| SCHEMBL11330858 | 0.70 | MAPT (0.55) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL30360237 | 0.70 | TDP1 (0.67) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL28977416 | 0.70 | TDP1 (0.67) | TDP1CYP1A2KMT2AMEN1LMNA | |
| SCHEMBL11322900 | 0.69 | TDP1 (0.47) | TDP1CYP1A2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-09-18 | — | — | US | claimed |
| EP-4452214-A1 | COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023228870-A1 | COMPOSITION FOR COLORING KERATIN FIBERS | L'OREAL (FR) | 2023-11-30 | — | — | WO | disclosed |
| EP-4240311-A1 | COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2023-09-13 | — | — | EP | disclosed |
| WO-2023106218-A1 | COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2023-06-15 | — | — | WO | disclosed |
| CN-113795435-B | Soluble package of pre-measured powdered hair bleach | 莱雅公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022097742-A1 | COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022075204-A1 | COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2022-04-14 | — | — | WO | disclosed |
| EP-3233030-A1 | COMPOSITION IN THE FORM OF O/W EMULSION | L'OREAL (FR) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098786-A1 | COMPOSITION IN THE FORM OF O/W EMULSION | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
| WO-2012032673-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011027077-A2 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011027076-A2 | DYEING METHOD CONSISTING IN APPLYING A METALLIC SALT AND A COMPOSITION CONTAINING A HYDROPHOBIC DYE AND A SPECIFIC COMPOUND | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| EP-1496849-A1 | COMPOSITION FOR THE OXIDATION DYEING OF HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2005-01-19 | — | — | EP | disclosed |
| EP-1458338-A2 | DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003084495-A1 | COMPOSITION FOR THE OXIDATION DYEING OF HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2003-10-16 | — | — | WO | disclosed |
| WO-2003053329-A2 | DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE | L'OREAL (FR) | 2003-07-03 | — | — | WO | disclosed |
| US-6579326-B2 | For dyeing hair | L'OREAL S.A. (FR) | 2003-06-17 | — | — | US | disclosed |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | BRETON PHILIPPE (FR) | 2001-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | KRT18, INMT, KMO | TDP1 2965/4885CYP1A2 2076/4885KMT2A 1057/4885 |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | AOC1, DPYD, NDUFB4 | TDP1 264/4885CYP1A2 591/4885KMT2A 3305/4885 |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | KRT18, INMT, KMO | TDP1 3046/4885CYP1A2 2082/4885KMT2A 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.