Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4612966 | 0.98 | HSP90AA1 (0.42) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL29654019 | 0.86 | HSP90AA1 (0.46) | HSP90AA1ALDH1A1TSHRNOS1HSD17B10 | |
| SCHEMBL6871106 | 0.85 | HSP90AA1 (0.43) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL11896552 | 0.82 | GCK (0.50) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL999144 | 0.82 | SRC (0.42) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL996582 | 0.82 | F2RL1 (0.49) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL11484681 | 0.82 | HSP90AA1 (0.41) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL2652072 | 0.82 | HSP90AA1 (0.41) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| SCHEMBL11903297 | 0.82 | ENPP3 (0.42) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10517968 | 0.81 | F2RL1 (0.48) | HSP90AA1PDPK1LOXL2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112073-A1 | COMPOSITIONS AND METHODS RELATING TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING COMPOUNDS AND TARGETS THEREOF | DUKE UNIVERSITY (US) | 2011-05-12 | — | — | US | claimed |
| US-7678158-B2 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | THE PROCTER & GAMBLE COMPANY (US) | 2010-03-16 | — | — | US | claimed |
| US-20090144914-A1 | COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS | LIM MU LLL | 2009-06-11 | — | — | US | claimed |
| US-7507262-B2 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | THE PROCTER & GAMBLE COMPANY (US) | 2009-03-24 | — | — | US | claimed |
| EP-2018146-A2 | COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS | The Procter and Gamble Company (US) | 2009-01-28 | — | — | EP | claimed |
| EP-1351945-B1 | NOVEL 1,4-DIAMINO-2-(THIAZOL-2-YL)BENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2007102126-A2 | COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2007-09-13 | — | — | WO | claimed |
| US-20070209123-A1 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | THE PROCTER & GAMBLE COMPANY | 2007-09-13 | — | — | US | claimed |
| US-6875873-B2 | 1,4-Diamino-2-(thiazol-2-yl)benzene derivatives, and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-04-05 | — | — | US | claimed |
| US-20030115683-A1 | Novel 1,4-diamino-2-(thiazol-2-yl)benzene derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | claimed |
| US-12133906-B2 | Delivery particle | THE PROCTER & GAMBLE COMPANY (US) | 2024-11-05 | — | — | US | disclosed |
| US-20220409497-A1 | DELIVERY PARTICLE | PROCTER & GAMBLE (US) | 2022-12-29 | — | — | US | disclosed |
| EP-3733827-A1 | DELIVERY PARTICLES | The Procter & Gamble Company (US) | 2020-11-04 | — | — | EP | disclosed |
| EP-2563508-B1 | DELIVERY PARTICLE | PROCTER & GAMBLE (US) | 2019-07-10 | — | — | EP | disclosed |
| EP-1642563-B1 | Method of rapid hair dyeing | NOXELL CORP (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20030115683-A1 | Novel 1,4-diamino-2-(thiazol-2-yl)benzene derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | disclosed |
| US-20030115683-A1 | Novel 1,4-diamino-2-(thiazol-2-yl)benzene derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | disclosed |
| US-20030115683-A1 | Novel 1,4-diamino-2-(thiazol-2-yl)benzene derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | disclosed |
| WO-2002057243-A1 | NOVEL 1,4-DIAMINO-2-(THIAZOL-2-YL)BENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-07-25 | — | — | WO | disclosed |
| EP-0116297-A2 | Polyimide laminate with peel-resistance and method of manufacturing it | Akzo GmbH (DE) | 1984-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220409497-A1 | DELIVERY PARTICLE | LIPA, CHMP4B, SLC46A1 | HSP90AA1 269/4885PDPK1 3029/4885LOXL2 1125/4885 |
| US-20110112073-A1 | COMPOSITIONS AND METHODS RELATING TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING COMPOUNDS AND TARGETS THEREOF | HSF1, HSP90AB1, HSPBP1 | HSP90AA1 4/4885PDPK1 2370/4885LOXL2 4688/4885 |
| US-20090144914-A1 | COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS | KRT18, AKR7A2, AKR1C4 | HSP90AA1 3166/4885PDPK1 3985/4885LOXL2 1603/4885 |
| US-20030115683-A1 | Novel 1,4-diamino-2-(thiazol-2-yl)benzene derivatives and dyes containing said compounds | KRT18, DSP, TUBB1 | HSP90AA1 1147/4885PDPK1 2136/4885LOXL2 805/4885 |
| US-12133906-B2 | Delivery particle | LIPA, CHMP4B, SLC46A1 | HSP90AA1 269/4885PDPK1 3029/4885LOXL2 1125/4885 |
| US-20070209123-A1 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | KRT18, AKR7A2, AKR1C4 | HSP90AA1 3166/4885PDPK1 3985/4885LOXL2 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.