Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577615 | 0.78 | ALDH1A1 (0.38) | CYP2C9ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL213000 | 0.78 | KDM4E (0.44) | CYP2C9ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL31385433 | 0.74 | MAPT (0.50) | CYP2C9ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL31385413 | 0.74 | RORC (0.44) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TSHR | |
| SCHEMBL31356459 | 0.74 | NOTUM (0.44) | CYP2C9ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL20344535 | 0.70 | CYP1A2 (0.44) | ALDH1A1KDM4EHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL31385470 | 0.70 | KDM4E (0.45) | CYP2C9ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8736484 | 0.70 | LOXL2 (0.56) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TSHR | |
| SCHEMBL21843484 | 0.69 | POLB (0.47) | CYP2C9ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6389243 | 0.68 | LOXL2 (0.60) | ALDH1A1KDM4ESMN1; SMN2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269240-A1 | Novel Adenine Compound | Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1939199-A1 | NOVEL ADENINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269240-A1 | Novel Adenine Compound | ADORA1, ADORA2A, ADORA3 | CYP2C9 218/4885ALDH1A1 97/4885KDM4E 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.