Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334270 | 0.79 | — | — | |
| SCHEMBL1567062 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL9397825 | 0.78 | — | — | |
| SCHEMBL5244051 | 0.78 | MAOA (0.30) | — | |
| SCHEMBL6137372 | 0.76 | MAOA (0.31) | — | |
| SCHEMBL10806726 | 0.75 | MAOA (0.31) | — | |
| SCHEMBL6137250 | 0.75 | MAOA (0.31) | — | |
| SCHEMBL13917448 | 0.72 | L3MBTL1 (0.37) | L3MBTL1ZDHHC20 | |
| SCHEMBL15292867 | 0.72 | ADRB2 (0.38) | — | |
| SCHEMBL3482445 | 0.72 | ADRB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-A | 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2022-05-06 | — | — | CN | disclosed |
| EP-3174539-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | Pharmacyclics, LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016019233-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2016-02-04 | — | — | WO | disclosed |
| EP-2613785-A1 | HETEROARYLMETHYL AMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-07-17 | — | — | EP | disclosed |
| EP-2459572-A2 | SPIROCYCLIC AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2012-06-06 | — | — | EP | disclosed |
| WO-2012032018-A1 | HETEROARYLMETHYL AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011012896-A2 | COMPOUNDS - 801 | ASTRAZENECA AB (SE) | 2011-02-03 | — | — | WO | disclosed |
| WO-2008121640-A1 | COLLOIDAL PARTICLES FOR LOTUS EFFECT | THE CLOROX COMPANY (US) | 2008-10-09 | — | — | WO | disclosed |
| CN-1192102-C | Enzyme catalyzed therapeutic agents | NEWBIOTIC INC (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1291228-A | Enzyme catalyzed therapeutic agents | NEWBIOTIC INC (US) | 2001-04-11 | — | — | CN | disclosed |