SCHEMBL6137372

SCHEMBL6137372

C#CCCCCO[Si](C)(C)CCCC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6137250 0.98 MAOA (0.31) MAOAMAOB
SCHEMBL10806726 0.98 MAOA (0.31) MAOAMAOB
SCHEMBL5244051 0.94 MAOA (0.30) MAOAMAOB
SCHEMBL10334270 0.89
SCHEMBL8161878 0.82 CA1 (0.33)
Fluoride SCHEMBL27902336 0.80 ALDH1A1 (0.32)
SCHEMBL15292867 0.80 ADRB2 (0.38)
SCHEMBL15984917 0.78 CA1 (0.33)
Fluoride SCHEMBL28805747 0.78 ADRB2 (0.36)
SCHEMBL457637 0.76 L3MBTL1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425258-A4 HYDROXYEICOSENOIC ACID ANALOGS TAISHO PHARMACEUTICAL CO LTD (JP) 2005-02-16 EP disclosed
EP-1425258-A2 HYDROXYEICOSENOIC ACID ANALOGS TAISHO PHARMACEUTICAL CO., LTD (JP) 2004-06-09 EP disclosed
WO-2003024390-A2 HYDROXYEICOSENOIC ACID ANALOGS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2003-03-27 WO disclosed