Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715258 | 0.78 | GAA (0.41) | ADRB1HTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL6407806 | 0.75 | P2RX7 (0.31) | — | |
| SCHEMBL6407367 | 0.74 | — | — | |
| SCHEMBL6407183 | 0.74 | — | — | |
| SCHEMBL24709283 | 0.71 | SIGMAR1 (0.54) | ADRB1TDP1MAPTALOX5 | |
| Bromide SCHEMBL31141400 | 0.69 | SIGMAR1 (0.52) | ADRB1TDP1MAPTALOX5 | |
| SCHEMBL6408708 | 0.68 | — | — | |
| SCHEMBL19357378 | 0.68 | SLC6A4 (0.48) | ADRB1DRD2DRD3HTR2CHTR2B | |
| SCHEMBL10800951 | 0.67 | KEAP1 (0.44) | ADRB1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2581074 | 0.67 | CYP1A2 (0.40) | NOTUMALDH1A1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653259-B2 | Process for synthesizing heterocyclic compounds | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-02-18 | — | — | US | disclosed |
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | TST, NISCH, CLIC4 | ADRB1 3908/4885DRD2 2841/4885DRD3 3797/4885 |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | TST, NISCH, CLIC4 | ADRB1 3950/4885DRD2 2854/4885DRD3 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.