Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 14/20 | 0.59 |
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL20819144 | 0.99 | CASP1 (0.58) | CASP1CTSKCTSSCTSLCTSB | |
| SCHEMBL27919626 | 0.91 | CTSK (0.57) | CASP1CTSKCTSSCTSLCTSB | |
| SCHEMBL4280669 | 0.89 | CASP1 (0.67) | CASP1 | |
| SCHEMBL4280674 | 0.89 | CASP1 (0.67) | CASP1 | |
| SCHEMBL17114105 | 0.87 | CTSK (0.56) | CASP1CTSKCTSSCTSLCTSB | |
| SCHEMBL45470 | 0.87 | CTSK (0.56) | CASP1CTSKCTSSCTSLCTSB | |
| SCHEMBL20819127 | 0.87 | CTSK (0.56) | CASP1CTSKCTSSCTSLCTSB | |
| SCHEMBL18075229 | 0.87 | CTSK (0.65) | CTSKCTSSCTSLCTSB | |
| SCHEMBL29604402 | 0.87 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL18075231 | 0.87 | CTSK (0.65) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122743-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | Azevan Pharmaceuticals, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015148962-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | AZEVAN PHARMACEUTICALS, INC. (US) | 2015-10-01 | — | — | WO | disclosed |
| EP-2587919-A1 | METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER | Azevan Pharmaceuticals, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003436-A1 | METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER | AZEVAN PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |