Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17114105 | 1.00 | CTSK (0.56) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL45470 | 1.00 | CTSK (0.56) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL2921260 | 0.90 | FOLH1 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL677997 | 0.90 | FOLH1 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL7624700 | 0.90 | FOLH1 (0.59) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL3624634 | 0.87 | FOLH1 (0.55) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL7286347 | 0.87 | FOLH1 (0.55) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL45786 | 0.87 | CASP1 (0.59) | CTSKCTSSCTSLCTSBCASP1 | |
| SCHEMBL3624630 | 0.87 | FOLH1 (0.55) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL221391 | 0.87 | KYNU (0.60) | CTSKCTSSCTSLCTSBFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681871-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | Azevan Pharmaceuticals, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019055913-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | AZEVAN PHARMACEUTICALS, INC. (US) | 2019-03-21 | — | — | WO | disclosed |