SCHEMBL4578718

SCHEMBL4578718

O=S(=O)(OS(c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(O)cc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 16/20 0.48
CA2 P00918 16/20 0.48
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
LMNA P02545 1/20 0.37
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36
ENPP2 Q13822 1/20 0.36
GAA P10253 1/20 0.34
PKM P14618 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3141391 0.94 CA1 (0.44) CA1CA2MMP1MMP2MMP9
SCHEMBL3136040 0.93 CA1 (0.45) CA1CA2MMP1MMP2MMP9
SCHEMBL1615067 0.89 ESR1 (0.39) CA1CA2MMP2LMNACA12
SCHEMBL1802639 0.85 CA1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL271339 0.84 CA1 (0.44) CA1CA2CA12CA9GAA
SCHEMBL51400 0.83 CA1 (0.43) CA1CA2MMP1MMP2MMP9
SCHEMBL562808 0.83 CA1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL2158537 0.83 CA1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL4535203 0.82 CA2 (0.44) CA1CA2
SCHEMBL60138 0.82 CA2 (0.44) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11681227-B2 Enhanced EUV photoresist materials, formulations and processes IRRESISTIBLE MATERIALS LTD (GB) 2023-06-20 US disclosed
US-20200272050-A1 Enhanced EUV Photoresist Materials, Formulations and Processes IRRESISTIBLE MATERIALS, LTD (GB) 2020-08-27 US disclosed
US-10095112-B2 Multiple trigger photoresist compositions and methods IRRESISTIBLE MATERIALS LTD (GB) 2018-10-09 US disclosed
US-20180246408-A1 MULTIPLE TRIGGER PHOTORESIST COMPOSITIONS AND METHODS IRRESISTIBLE MATERIALS, LTD (GB) 2018-08-30 US disclosed
US-9519215-B2 Composition of matter and molecular resist made therefrom IRRESISTIBLE MATERIALS, LTD (GB) 2016-12-13 US disclosed
US-20160246173-A1 Composition of Matter and Molecular Resist Made Therefrom IRRESISTIBLE MATERIALS LTD (GB) 2016-08-25 US disclosed
US-9383646-B2 Two-step photoresist compositions and methods IRRESISTIBLE MATERIALS LTD (GB) 2016-07-05 US disclosed
US-9323149-B2 Methanofullerenes IRRESISTIBLE MATERIALS LTD (GB) 2016-04-26 US disclosed
US-9256126-B2 Methanofullerenes IRRESISTIBLE MATERIALS LTD (GB) 2016-02-09 US disclosed
US-9229322-B2 Composition of matter and molecular resist made therefrom IRRESISTIBLE MATERIALS LTD (GB) 2016-01-05 US disclosed
US-20150140489-A1 Composition of Matter and Molecular Resist Made Therefrom IRRESISTIBLE MATERIALS LTD (GB) 2015-05-21 US disclosed
WO-2014137663-A1 METHANOFULLERENES ROBINSON ALEX PHILIP GRAHAM (GB) 2014-09-12 WO disclosed
US-20140255849-A1 Methanofullerenes IRRESISTIBLE MATERIALS LTD (GB) 2014-09-11 US disclosed
WO-2014078097-A1 METHANOFULLERENES ROBINSON ALEX PHILIP GRAHAM (GB) 2014-05-22 WO disclosed
US-20140134843-A1 Methanofullerenes IRRESISTIBLE MATERIALS LTD (GB) 2014-05-15 US disclosed
US-7374860-B2 Positive resist composition and pattern forming method using the same FUJI FILM CORPORATION (JP) 2008-05-20 US disclosed
US-20060216635-A1 Positive resist composition and pattern forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-09-28 US disclosed
EP-1705518-A2 Positive resist composition and pattern forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-7078148-B2 Photoresist with improved sensitivity and resolution to deep ultraviolet rays/excimer lasers; semiconductors; integrated circuits JSR CORPORATION (JP) 2006-07-18 US disclosed
US-20040072094-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2004-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10095112-B2 Multiple trigger photoresist compositions and methods ERCC4, ERCC2, APEX1 CA1 2590/4885CA2 616/4885MMP1 2965/4885
US-20140134843-A1 Methanofullerenes WASF2, ERCC4, TUFM CA1 4687/4885CA2 4656/4885MMP1 4595/4885
US-20150140489-A1 Composition of Matter and Molecular Resist Made Therefrom HNRNPM, TUFM, MSR1 CA1 642/4885CA2 860/4885MMP1 3730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.