SCHEMBL4579781

SCHEMBL4579781

CCNc1ccc(C(C)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
MCL1 Q07820 1/20 0.51
NOX1 Q9Y5S8 1/20 0.51
NPC1 O15118 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
RAB9A P51151 4/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALDH1A1 P00352 2/20 0.49
HTT P42858 2/20 0.48
NLRP1 Q9C000 1/20 0.48
HPGD P15428 3/20 0.47
CYP1A1 P04798 1/20 0.47
CYP1B1 Q16678 1/20 0.47
MAPK1 P28482 1/20 0.46
LMNA P02545 2/20 0.46
ADRA2A P08913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19822982 0.89 CYP1A1 (0.60) MAPTKMT2AMEN1POLBGAA
SCHEMBL51622 0.84 ALDH1A1 (0.52) MAPTKMT2AMEN1POLBGAA
SCHEMBL14535153 0.83 NPC1 (0.49) MAPTKMT2AMEN1POLBGAA
SCHEMBL455156 0.83 HCAR3 (0.55) MAPTKMT2APOLBGAASMN1; SMN2
SCHEMBL8418608 0.82 ADRA2A (0.53) MAPTKMT2AMEN1POLBGAA
SCHEMBL6776537 0.81 MAPT (0.46) MAPTKMT2AMEN1POLBGAA
SCHEMBL10084799 0.81 MAPT (0.52) MAPTKMT2AMEN1POLBGAA
SCHEMBL1803092 0.81 ADRA2A (0.53) MAPTKMT2AMEN1POLBGAA
SCHEMBL10997394 0.80 LMNA (0.56) MAPTKMT2AMEN1POLBGAA
Oxalic Acid SCHEMBL9716123 0.79 LMNA (0.55) MAPTKMT2AMEN1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118108-A Preparation method and application of near infrared nitric oxide probe 山东第一医科大学(山东省医学科学院) 2025-06-10 CN disclosed
EP-3116935-B1 NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE UNIV COLORADO REGENTS (US) 2024-06-19 EP disclosed
CN-111778016-B Near infrared fluorescent probe and preparation method and application thereof 深圳大学 2023-06-23 CN disclosed
CN-111978247-B Two-photon fluorescent probe and preparation method and application thereof 深圳大学 2022-01-25 CN disclosed
CN-111978247-A Two-photon fluorescent probe and preparation method and application thereof 深圳大学 2020-11-24 CN disclosed
CN-111778016-A Near-infrared fluorescent probe and preparation method and application thereof 深圳大学 2020-10-16 CN disclosed
US-20170237119-A1 LI-ION ELECTROLYTE MEMBRANE FACILITATED BY A SELF-HEALING POLYMER MATRIX, AND ASSOCIATED BATTERY UNIV COLORADO REGENTS (US) 2017-08-17 US disclosed
EP-3116935-A1 NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE The Regents of the University of Colorado, a body corporate (US) 2017-01-18 EP disclosed
US-9453099-B2 Covalently cross-linked malleable polymers and methods of use THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2016-09-27 US disclosed
WO-2015138804-A1 NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE THE REGENTS OF THE UNIVERITY OF COLORADO, A BODY CORPORATE (US) 2015-09-17 WO disclosed
US-7297695-B2 Pyrrolotriazine compounds as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2007-11-20 US disclosed
US-20070093502-A1 5- Or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication BONFANTI JEAN-FRANCOIS 2007-04-26 US disclosed
US-20070093502-A1 5- Or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication BONFANTI JEAN-FRANCOIS 2007-04-26 US disclosed
US-20050065246-A1 Novel azo compound, colorant-containing curable composition, and color filter and method of producing the same FUJI PHOTO FILM CO., LTD. 2005-03-24 US disclosed
EP-0878196-B1 KAINIC ACID NEURONOTOXICITY INHIBITORS AND PYRIDOTHIAZINE DERIVATIVES YAMANOUCHI PHARMA CO LTD (JP) 2003-09-03 EP disclosed
US-6133258-A PYRIDOTHIAZINE DERIVATIVE; FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS, MULTIPLE SCLEROSIS, PAIN, GLAUCOMA YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 2000-10-17 US disclosed
EP-0878196-A1 KAINIC ACID NEURONOTOXICITY INHIBITORS AND PYRIDOTHIAZINE DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-11-18 EP disclosed
US-4145363-A ANTIASTHMATICS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1979-03-20 US disclosed
US-4142783-A Reversible electrochromic display device having memory INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-03-06 US disclosed
US-4063025-A PROPHYLAXIS, ANTIASTHMATIC YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093502-A1 5- Or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, SUB1, HYOU1 MAPT 4884/4885KMT2A 869/4885MEN1 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.