Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024699 | 0.86 | GPR3 (0.32) | GPR3 | |
| SCHEMBL1361401 | 0.82 | TRPV1 (0.37) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1360496 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1510479 | 0.75 | PGR (0.39) | GPR3KIF11MAPTEPHX2GAA | |
| SCHEMBL12160006 | 0.75 | PGR (0.39) | GPR3KIF11MAPTEPHX2GAA | |
| SCHEMBL457747 | 0.74 | GPR3 (0.40) | GPR3KIF11MAPTEPHX2GAA | |
| SCHEMBL1024765 | 0.73 | GPR3 (0.38) | GPR3KIF11MAPTEPHX2GAA | |
| SCHEMBL2253244 | 0.73 | GPR3 (0.38) | GPR3KIF11MAPTEPHX2GAA | |
| SCHEMBL22926343 | 0.73 | PGR (0.34) | GPR3 | |
| SCHEMBL17157399 | 0.71 | GPR3 (0.42) | GPR3KIF11MAPTEPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891466-A | Pyrazole-containing dithiazole carboxamide derivative and preparation method and application thereof | 南开大学 | 2023-10-17 | — | — | CN | claimed |
| US-6638956-B2 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2003-10-28 | — | — | US | claimed |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2003-07-31 | — | — | US | claimed |
| US-6593328-B2 | Said compounds for the control of arthropod, nematode, helminth or protozoan pests, in particular to the application of said compounds or compositions in agricultural methods of use, particularly as pesticides, for controlling arthropods, | RHONE-POULENC INC. | 2003-07-15 | — | — | US | claimed |
| US-20030092680-A1 | Novel pesticides | WU TAI-TEH (US) | 2003-05-15 | — | — | US | claimed |
| US-20020173492-A1 | Novel pesticides | WU TAI-TEH (US) | 2002-11-21 | — | — | US | claimed |
| US-6376520-B1 | INSECTICIDES, NEMATOCIDES | RHONE-POULENC, INC. | 2002-04-23 | — | — | US | claimed |
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2002-04-18 | — | — | US | claimed |
| US-6350771-B1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2002-02-26 | — | — | US | claimed |
| US-6346522-B1 | 1-ARYLPYRAZOLES; SYSTEMIC PESTICIDES, INSECTICIDES, LARVICIDES, MITICIDES, ANTIPROTOZOA, AND ANTHELMINTIC AGENTS; AGRICULTURE, HORTICULTURE, ANIMAL HUSBANDRY, PUBLIC HEALTH AND VETERINARY MEDICINE | RHONE-POULENC, INC. | 2002-02-12 | — | — | US | claimed |
| US-6277848-B1 | Pesticides | RHONE-POULENC, INC. | 2001-08-21 | — | — | US | claimed |
| US-6107314-A | INSECTICIDES, NEMATOCIDES, PARASITICIDES | RHONE-POULENC INC. (US) | 2000-08-22 | — | — | US | claimed |
| US-5914335-A | INSECTICIDES | RHONE-POULENC INC. (US) | 1999-06-22 | — | — | US | claimed |
| EP-0911329-A1 | 3-Substituted arylpyrazole derivatives | RHONE-POULENC AGRO (FR) | 1999-04-28 | — | — | EP | claimed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | claimed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | claimed |
| CN-116891466-A | Pyrazole-containing dithiazole carboxamide derivative and preparation method and application thereof | 南开大学 | 2023-10-17 | — | — | CN | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173492-A1 | Novel pesticides | DDT, ACHE, PTMS | GPR3 1789/4885KIF11 3207/4885MAPT 3587/4885 |
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | GPR3 1191/4885KIF11 4050/4885MAPT 4318/4885 |
| US-20030144251-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | GPR3 1191/4885KIF11 4050/4885MAPT 4318/4885 |
| US-20030092680-A1 | Novel pesticides | DDT, ACHE, PTMS | GPR3 1789/4885KIF11 3207/4885MAPT 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.