Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21630284 | 0.88 | EPHX2 (0.36) | GPR3MAPTSLC6A2SLC6A3SCN5A | |
| SCHEMBL407346 | 0.78 | GPR3 (0.41) | GPR3KIF11CES1GAAALOX15 | |
| SCHEMBL1067722 | 0.78 | ALOX15 (0.39) | ALDH1A1POLBALOX15NPC1RAB9A | |
| SCHEMBL622940 | 0.78 | GPR3 (0.41) | GPR3KIF11CES1GAAALOX15 | |
| SCHEMBL1067461 | 0.77 | GPR3 (0.38) | GPR3KIF11CES1GAAALOX15 | |
| SCHEMBL538958 | 0.76 | GPR3 (0.41) | GPR3KIF11CES1GAAPOLB | |
| SCHEMBL3076523 | 0.76 | GPR3 (0.40) | GPR3KIF11CES1GAAALOX15 | |
| SCHEMBL407097 | 0.76 | GPR3 (0.40) | GPR3KIF11CES1GAAALOX15 | |
| SCHEMBL1066922 | 0.76 | GPR3 (0.40) | GPR3KIF11CES1GAAALOX15 | |
| SCHEMBL1068998 | 0.76 | GPR3 (0.37) | GPR3KIF11CES1GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | claimed |
| EP-1603897-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2005-12-14 | — | — | EP | claimed |
| WO-2004080999-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2004-09-23 | — | — | WO | claimed |
| CN-1400970-A | Substituted arylpyrazines | NEUROGEN CORP (US) | 2003-03-05 | — | — | CN | claimed |
| US-5556873-A | AGRICULTURAL PESTICIDES | RHONE-POULENC INC. (US) | 1996-09-17 | — | — | US | claimed |
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-23 | — | — | US | disclosed |
| CN-113347883-B | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-113347883-A | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-0511845-B1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | AVENTIS CROPSCIENCE SA (FR) | 2001-10-31 | — | — | EP | disclosed |
| US-6046195-A | Spiro-azacyclic derivatives, their preparation and their use as tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 2000-04-04 | — | — | US | disclosed |
| US-5556873-A | AGRICULTURAL PESTICIDES | RHONE-POULENC INC. (US) | 1996-09-17 | — | — | US | disclosed |
| US-5360910-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC AG COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5321040-A | Pesticidal 1-aryl-5-(substituted N-cinnamylideneimino) pyrazoles | RHONE-POULENC INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0511845-A1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1992-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | DGKZ, DGKA, DGKG | GPR3 643/4885KIF11 3976/4885CES1 1403/4885 |
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | GPR3 1451/4885KIF11 4865/4885CES1 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.