SCHEMBL4580676

SCHEMBL4580676

O=C(O)c1ccccc1C(=O)OC1(c2ccccc2)CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 1/20 0.44
AKR1C1 Q04828 1/20 0.42
HDAC4 P56524 2/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
AKR1C3 P42330 1/20 0.37
HSD11B1 P28845 1/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36
PDE3A Q14432 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580673 0.95 AKR1C1 (0.46) ALDH1A1AKR1C1HDAC4MEN1KMT2A
SCHEMBL27524375 0.88 ALDH1A1 (0.44) ALDH1A1ALOX15AKR1C1HDAC4MEN1
SCHEMBL27593585 0.82 LMNA (0.48) AKR1C1HDAC4CYP3A4CYP2D6CYP2C9
SCHEMBL4580279 0.82 AKR1C1 (0.46) ALDH1A1AKR1C1HDAC4CYP3A4CYP2D6
SCHEMBL4580283 0.81 AKR1C1 (0.42) AKR1C1HDAC4CYP3A4CYP2D6CYP2C9
SCHEMBL28492099 0.81 ALDH1A1 (0.47) ALDH1A1ALOX15AKR1C1CYP3A4CYP2D6
SCHEMBL9191673 0.80 AKR1C1 (0.50) AKR1C1HDAC4MEN1KMT2AHSD11B1
SCHEMBL9191670 0.80 AKR1C1 (0.50) AKR1C1HDAC4MEN1KMT2AHSD11B1
SCHEMBL6404697 0.79 SCN1A (0.51) ALDH1A1ALOX15CYP3A4CYP2D6CYP2C9
SCHEMBL4580640 0.78 AKR1C1 (0.42) ALDH1A1AKR1C1HDAC4TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed