SCHEMBL4580640

SCHEMBL4580640

O=C(OC1(c2ccccc2)CCCCC1)c1cccc(C(=O)OC2(c3ccccc3)CCCCC2)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.42
HDAC4 P56524 2/20 0.41
LMNA P02545 2/20 0.40
F2 P00734 1/20 0.40
ALDH1A1 P00352 3/20 0.40
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
DRD3 P35462 1/20 0.38
HSD11B1 P28845 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580643 0.96 AKR1C3 (0.41) AKR1C1HDAC4LMNAF2ALDH1A1
SCHEMBL27593585 0.92 LMNA (0.48) AKR1C1HDAC4LMNAF2SMN1; SMN2
SCHEMBL4580279 0.89 AKR1C1 (0.46) AKR1C1HDAC4LMNAF2ALDH1A1
SCHEMBL10687586 0.87 LMNA (0.50) AKR1C1HDAC4LMNAF2ALDH1A1
SCHEMBL4580283 0.84 AKR1C1 (0.42) AKR1C1HDAC4LMNAF2SMN1; SMN2
SCHEMBL4580673 0.82 AKR1C1 (0.46) AKR1C1HDAC4LMNAALDH1A1SMN1; SMN2
SCHEMBL14062595 0.82 L3MBTL1 (0.43) AKR1C1LMNAF2ALDH1A1NPSR1
SCHEMBL27516395 0.81 CES2 (0.45) LMNAALDH1A1SMN1; SMN2TDP1KMT2A
SCHEMBL9191670 0.80 AKR1C1 (0.50) AKR1C1HDAC4SMN1; SMN2KMT2AMEN1
SCHEMBL9191673 0.80 AKR1C1 (0.50) AKR1C1HDAC4SMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed