SCHEMBL4580283

SCHEMBL4580283

O=C(O)c1ccc(C(=O)OC2(c3ccccc3)CCCCC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.42
HDAC4 P56524 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 2/20 0.40
F2 P00734 1/20 0.40
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
SRD5A2 P31213 2/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HDAC1 Q13547 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580279 0.95 AKR1C1 (0.46) AKR1C1HDAC4MEN1KMT2ACYP1A2
SCHEMBL27593585 0.92 LMNA (0.48) AKR1C1HDAC4MEN1KMT2ACYP1A2
SCHEMBL10687586 0.87 LMNA (0.50) AKR1C1HDAC4MEN1KMT2ACYP1A2
SCHEMBL4580643 0.87 AKR1C3 (0.41) AKR1C1HDAC4MEN1KMT2ACYP2D6
SCHEMBL4580640 0.84 AKR1C1 (0.42) AKR1C1HDAC4MEN1KMT2ASMN1; SMN2
SCHEMBL24262285 0.84 TAS1R3 (0.38) AKR1C1HDAC4MEN1KMT2ACYP1A2
SCHEMBL24715987 0.82 TAS1R3 (0.38) AKR1C1HDAC4MEN1KMT2ACYP1A2
SCHEMBL4580673 0.82 AKR1C1 (0.46) AKR1C1HDAC4MEN1KMT2ASMN1; SMN2
SCHEMBL14062595 0.82 L3MBTL1 (0.43) AKR1C1MEN1KMT2ACYP1A2CYP3A4
SCHEMBL4580676 0.81 ALDH1A1 (0.44) AKR1C1HDAC4MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed