SCHEMBL4580279

SCHEMBL4580279

O=C(OC1(c2ccccc2)CCCCC1)c1ccc(C(=O)OC2(c3ccccc3)CCCCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.46
LMNA P02545 3/20 0.44
F2 P00734 1/20 0.44
HDAC4 P56524 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HDAC1 Q13547 2/20 0.40
HSD11B1 P28845 1/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27593585 0.97 LMNA (0.48) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL4580283 0.95 AKR1C1 (0.42) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL10687586 0.91 LMNA (0.50) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL4580640 0.89 AKR1C1 (0.42) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL24262285 0.89 TAS1R3 (0.38) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL24715987 0.87 TAS1R3 (0.38) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL4580673 0.86 AKR1C1 (0.46) AKR1C1LMNAHDAC4SMN1; SMN2MEN1
SCHEMBL14062595 0.86 L3MBTL1 (0.43) AKR1C1LMNAF2MEN1KMT2A
SCHEMBL4580643 0.85 AKR1C3 (0.41) AKR1C1LMNAF2HDAC4SMN1; SMN2
SCHEMBL25834165 0.84 CYP2C9 (0.41) LMNASMN1; SMN2MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed