SCHEMBL4580682

SCHEMBL4580682

O=C(O)C1C(Cc2ccccc2)CCCC1(Cc1ccccc1)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 3/20 0.36
LTB4R2 Q9NPC1 3/20 0.36
MME P08473 1/20 0.36
SLC1A2 P43004 1/20 0.36
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTGS1 P23219 7/20 0.34
PTGS2 P35354 6/20 0.34
MT-CO1 P00395 1/20 0.34
MT-CO2 P00403 1/20 0.34
TMEM97 Q5BJF2 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
HSD11B1 P28845 1/20 0.33
EPHX1 P07099 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060766 0.77 HPGD (0.38) ALDH1A1LMNASMN1; SMN2HSD11B1EPHX1
SCHEMBL23927666 0.71 HSD11B1 (0.36) HSD11B1
SCHEMBL23927601 0.71 HSD11B1 (0.36) HSD11B1
SCHEMBL16167219 0.70 AKR1C3 (0.38) ALDH1A1LMNASMN1; SMN2HSD11B1HPGD
SCHEMBL7447229 0.69 KDM4E (0.40) ALDH1A1SMN1; SMN2EPHX1HPGD
SCHEMBL7452644 0.68 TAAR1 (0.53) ALDH1A1LMNASMN1; SMN2HSD11B1
SCHEMBL7452648 0.68 TAAR1 (0.53) ALDH1A1LMNASMN1; SMN2HSD11B1
SCHEMBL7230439 0.68 TAAR1 (0.53) ALDH1A1LMNASMN1; SMN2HSD11B1
SCHEMBL31015736 0.67 TRPA1 (0.41) LTB4RLTB4R2MMEALDH1A1LMNA
SCHEMBL1841591 0.66 LMNA (0.46) ALDH1A1LMNAHSD11B1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed