SCHEMBL4580791

SCHEMBL4580791

FC(F)(Br)C(F)(F)Oc1ccc(-c2ccc(OC(F)(F)C(F)(F)Br)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.39
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
SCN5A Q14524 10/20 0.36
AURKA O14965 1/20 0.36
TPX2 Q9ULW0 1/20 0.36
NISCH Q9Y2I1 1/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
CHEK1 O14757 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4323037 0.83 CYP2A6 (0.38) KIF11CA9
SCHEMBL9171548 0.81 CA1 (0.50) CA12CA9
SCHEMBL9171098 0.81 ALDH1A1 (0.44) KIF11
SCHEMBL12200950 0.81 ACHE (0.42) CA9
SCHEMBL6468423 0.80 LTA4H (0.39) KIF11
SCHEMBL18784105 0.78 KIF11 (0.38) KIF11CA12CA9SCN5AAURKA
SCHEMBL9352394 0.78 TRPV1 (0.35)
SCHEMBL9799373 0.76
SCHEMBL5312032 0.76 PPARG (0.45)
SCHEMBL9006624 0.76 ALDH1A1 (0.47) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492460-B2 Fluorinated polymer blocks for PEM applications GM Global Technology Operations LLC (US) 2013-07-23 US disclosed
US-20080027152-A1 Fluorinated Polymer Blocks For PEM Applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2008-01-31 US disclosed
WO-2007052954-A1 BLOCK COPOLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS AND ELECTROLYTE MEMBRANES USING THE SAME LG CHEM, LTD. (KR) 2007-05-10 WO disclosed
EP-1286961-B1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES CO (US) 2004-05-19 EP disclosed
EP-1286961-A1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M Innovative Properties Company (US) 2003-03-05 EP disclosed
US-6384167-B2 MECHANICAL PROPERTIES ALONG WITH A DESIRABLE LEVEL OF IONIC CONDUCTIVITY; ION-EXCHANGE MEMBRANES 3M INNOVATIVE PROPERTIES COMPANY 2002-05-07 US disclosed
US-20020007083-A1 Sulfonated perfluorovinyl functional monomers 3M INNOVATIVE PROPERTIES COMPANY 2002-01-17 US disclosed
WO-2001094305-A1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-13 WO disclosed
US-6268532-B1 USED FOR PREPARING SULFONATED OR NON-SULFONATED BLOCK POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-07-31 US disclosed
US-5364917-A Perfluorocyclobutane ring-containing polymers THE DOW CHEMICAL COMPANY (US) 1994-11-15 US disclosed
US-5159037-A Crosslinking THE DOW CHEMICAL COMPANY (US) 1992-10-27 US disclosed
US-5159036-A Dimerizing perfluorovinyl groups, heating, crosslinking THE DOW CHEMICAL COMPANY (US) 1992-10-27 US disclosed
US-5066746-A Dielectric Fluids, Lubricants And Plastics THE DOW CHEMICAL COMPANY (US) 1991-11-19 US disclosed
US-5037917-A Polymerizing Monomers Containing At Least Two Perfluorovinyl Groups, Then Heating To Form Perfluorocyclobutane Rings THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
US-5037918-A Heating a monomer having two dimerizable perfluorovinyl groups and crosslinking THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
US-5023380-A Monomer for thermoplastic resin THE DOW CHEMICAL COMPANY (US) 1991-06-11 US disclosed
EP-0428708-A1 PROCESS FOR PREPARING A POLYMER HAVING PERFLUOROCYCLOBUTANE RINGS AND POLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS. DOW CHEMICAL CO (US) 1991-05-29 EP disclosed
EP-0428706-A1 PERFLUOROVINYL COMPOUNDS. DOW CHEMICAL CO (US) 1991-05-29 EP disclosed
WO-1990015043-A2 PERFLUOROVINYL COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1990-12-13 WO disclosed
WO-1990015082-A1 PROCESS FOR PREPARING A POLYMER HAVING PERFLUOROCYCLOBUTANE RINGS AND POLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1990-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007083-A1 Sulfonated perfluorovinyl functional monomers AFF2, AFF1, FOS KIF11 1645/4885CA12 1594/4885CA9 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.