Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215378 | 0.87 | TSHR (0.56) | POLBKMT2AMAPTMEN1AKR1C3 | |
| SCHEMBL460131 | 0.87 | TSHR (0.56) | POLBKMT2AMAPTMEN1AKR1C3 | |
| SCHEMBL16056351 | 0.85 | KMT2A (0.59) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL458612 | 0.84 | SLC22A12 (0.58) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL28158589 | 0.81 | AKR1C3 (0.57) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL16056241 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL459946 | 0.81 | HSD17B2 (0.47) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL460237 | 0.81 | HSD17B2 (0.57) | ALDH1A1KDM4EKMT2AMAPTRAB9A | |
| SCHEMBL5925578 | 0.80 | HSD17B2 (0.62) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL3559893 | 0.78 | TSHR (0.64) | ALDH1A1KDM4EPOLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10085957-B2 | Benzoic acid compounds for reducing uric acid | WELLSTAT THERAPEUTICS CORPORATION (US) | 2018-10-02 | — | — | US | disclosed |
| US-20170042844-A1 | BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID | PHARMA CINQ, LLC | 2017-02-16 | — | — | US | disclosed |
| US-20130331452-A1 | BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-12-12 | — | — | US | disclosed |
| WO-2012033720-A1 | BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10085957-B2 | Benzoic acid compounds for reducing uric acid | FPR1, FFAR1, GLS | ALDH1A1 3749/4885KDM4E 1298/4885POLB 3137/4885 |
| US-20130331452-A1 | BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID | GLS, NLRP3, XDH | ALDH1A1 2683/4885KDM4E 1362/4885POLB 3467/4885 |
| US-20170042844-A1 | BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID | FPR1, FFAR1, GLS | ALDH1A1 3749/4885KDM4E 1298/4885POLB 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.